Abstract

Stem cell (SC) therapy has a promising future for tissue regenerative medicine. However, because SC technology is still in its infancy, interdisciplinary cooperation is needed to achieve successful clinical applications. Dental SCs have drawn attention in recent years because of their accessibility, plasticity, and high proliferative ability. Several types of dental SCs have been identified, including dental pulp SCs from adult human dental pulp, SCs from human primary exfoliated deciduous teeth, periodontal ligament SCs, and dental follicle SCs from human third molars. Similar to mesenchymal SCs, these dental SCs can undergo self-renewal and have multipotent differentiation ability, but do not have the ethical issues associated with other sources of SCs. Therefore, appropriate preservation procedures for dental SCs and teeth are now needed. Here, we discuss the opportunities for tooth-banking (as it is now clinically feasible and commercially available), the advantages and limitations of current cryopreservation techniques for dental SCs/teeth or tissues, and the current status of tooth banks.

Original languageEnglish
Pages (from-to)111-117
Number of pages7
JournalJournal of Experimental and Clinical Medicine(Taiwan)
Volume2
Issue number3
DOIs
Publication statusPublished - Jun 2010

Fingerprint

Regenerative Medicine
Tooth
Stem Cells
Dental Pulp
Dental Sac
Periodontal Ligament
Third Molar
Deciduous Tooth
Cryopreservation
Cell- and Tissue-Based Therapy
Ethics
Technology

Keywords

  • Cryopreservation
  • Dental stem cell
  • Stem cell therapy
  • Tooth bank

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Dental Stem Cells and Tooth Banking for Regenerative Medicine. / Huang, Yen-Hua; Yang, Jen-Chang; Wang, Chin Wei; Lee, Sheng-Yang.

In: Journal of Experimental and Clinical Medicine(Taiwan), Vol. 2, No. 3, 06.2010, p. 111-117.

Research output: Contribution to journalReview article

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N2 - Stem cell (SC) therapy has a promising future for tissue regenerative medicine. However, because SC technology is still in its infancy, interdisciplinary cooperation is needed to achieve successful clinical applications. Dental SCs have drawn attention in recent years because of their accessibility, plasticity, and high proliferative ability. Several types of dental SCs have been identified, including dental pulp SCs from adult human dental pulp, SCs from human primary exfoliated deciduous teeth, periodontal ligament SCs, and dental follicle SCs from human third molars. Similar to mesenchymal SCs, these dental SCs can undergo self-renewal and have multipotent differentiation ability, but do not have the ethical issues associated with other sources of SCs. Therefore, appropriate preservation procedures for dental SCs and teeth are now needed. Here, we discuss the opportunities for tooth-banking (as it is now clinically feasible and commercially available), the advantages and limitations of current cryopreservation techniques for dental SCs/teeth or tissues, and the current status of tooth banks.

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