Abstract

Purpose Previous epidemiologic studies that focused on the association between open-angle glaucoma (OAG) and dementia showed inconsistent results. In the present study, we explored the association between OAG and dementia in an ethnic Chinese (ie, Taiwanese) population using a population-based data set.MethodsWe retrieved data on study subjects for this case-control study from the Longitudinal Health Insurance Database 2000. We identified 7770 patients who had a diagnosis of dementia as cases, and 7770 subjects matched in terms of sex and age, which were randomly extracted as controls. A conditional logistic regression conditioned on age group, sex, and index year was used to assess the association of dementia with previously diagnosed OAG among the sampled patients.ResultsOf 15 540 patients, 1.70% had prior OAG, including 2.02% of the dementia group and 1.38% of the controls. After adjusting for patient socioeconomic characteristics and comorbid medical disorders, dementia patients were more likely to have had prior OAG than controls (odds ratio (OR): 1.44; 95% confidence interval (CI): 1.12-1.85; P

Original languageEnglish
Pages (from-to)1340-1346
Number of pages7
JournalEye
Volume29
Issue number10
DOIs
Publication statusPublished - Oct 1 2015

Fingerprint

Open Angle Glaucoma
Dementia
Population
Health Insurance
Case-Control Studies
Epidemiologic Studies
Age Groups
Logistic Models
Odds Ratio
Databases
Confidence Intervals
Control Groups

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Dementia is associated with open-angle glaucoma : A population-based study. / Chung, S. D.; Ho, J. D.; Chen, C. H.; Lin, H. C.; Tsai, M. C.; Sheu, J. J.

In: Eye, Vol. 29, No. 10, 01.10.2015, p. 1340-1346.

Research output: Contribution to journalArticle

Chung, S. D. ; Ho, J. D. ; Chen, C. H. ; Lin, H. C. ; Tsai, M. C. ; Sheu, J. J. / Dementia is associated with open-angle glaucoma : A population-based study. In: Eye. 2015 ; Vol. 29, No. 10. pp. 1340-1346.
@article{dcd8d40f14be4417a54dbdd83e3bc6d9,
title = "Dementia is associated with open-angle glaucoma: A population-based study",
abstract = "Purpose Previous epidemiologic studies that focused on the association between open-angle glaucoma (OAG) and dementia showed inconsistent results. In the present study, we explored the association between OAG and dementia in an ethnic Chinese (ie, Taiwanese) population using a population-based data set.MethodsWe retrieved data on study subjects for this case-control study from the Longitudinal Health Insurance Database 2000. We identified 7770 patients who had a diagnosis of dementia as cases, and 7770 subjects matched in terms of sex and age, which were randomly extracted as controls. A conditional logistic regression conditioned on age group, sex, and index year was used to assess the association of dementia with previously diagnosed OAG among the sampled patients.ResultsOf 15 540 patients, 1.70{\%} had prior OAG, including 2.02{\%} of the dementia group and 1.38{\%} of the controls. After adjusting for patient socioeconomic characteristics and comorbid medical disorders, dementia patients were more likely to have had prior OAG than controls (odds ratio (OR): 1.44; 95{\%} confidence interval (CI): 1.12-1.85; P",
author = "Chung, {S. D.} and Ho, {J. D.} and Chen, {C. H.} and Lin, {H. C.} and Tsai, {M. C.} and Sheu, {J. J.}",
year = "2015",
month = "10",
day = "1",
doi = "10.1038/eye.2015.120",
language = "English",
volume = "29",
pages = "1340--1346",
journal = "Eye",
issn = "0950-222X",
publisher = "Nature Publishing Group",
number = "10",

}

TY - JOUR

T1 - Dementia is associated with open-angle glaucoma

T2 - A population-based study

AU - Chung, S. D.

AU - Ho, J. D.

AU - Chen, C. H.

AU - Lin, H. C.

AU - Tsai, M. C.

AU - Sheu, J. J.

PY - 2015/10/1

Y1 - 2015/10/1

N2 - Purpose Previous epidemiologic studies that focused on the association between open-angle glaucoma (OAG) and dementia showed inconsistent results. In the present study, we explored the association between OAG and dementia in an ethnic Chinese (ie, Taiwanese) population using a population-based data set.MethodsWe retrieved data on study subjects for this case-control study from the Longitudinal Health Insurance Database 2000. We identified 7770 patients who had a diagnosis of dementia as cases, and 7770 subjects matched in terms of sex and age, which were randomly extracted as controls. A conditional logistic regression conditioned on age group, sex, and index year was used to assess the association of dementia with previously diagnosed OAG among the sampled patients.ResultsOf 15 540 patients, 1.70% had prior OAG, including 2.02% of the dementia group and 1.38% of the controls. After adjusting for patient socioeconomic characteristics and comorbid medical disorders, dementia patients were more likely to have had prior OAG than controls (odds ratio (OR): 1.44; 95% confidence interval (CI): 1.12-1.85; P

AB - Purpose Previous epidemiologic studies that focused on the association between open-angle glaucoma (OAG) and dementia showed inconsistent results. In the present study, we explored the association between OAG and dementia in an ethnic Chinese (ie, Taiwanese) population using a population-based data set.MethodsWe retrieved data on study subjects for this case-control study from the Longitudinal Health Insurance Database 2000. We identified 7770 patients who had a diagnosis of dementia as cases, and 7770 subjects matched in terms of sex and age, which were randomly extracted as controls. A conditional logistic regression conditioned on age group, sex, and index year was used to assess the association of dementia with previously diagnosed OAG among the sampled patients.ResultsOf 15 540 patients, 1.70% had prior OAG, including 2.02% of the dementia group and 1.38% of the controls. After adjusting for patient socioeconomic characteristics and comorbid medical disorders, dementia patients were more likely to have had prior OAG than controls (odds ratio (OR): 1.44; 95% confidence interval (CI): 1.12-1.85; P

UR - http://www.scopus.com/inward/record.url?scp=84943393830&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84943393830&partnerID=8YFLogxK

U2 - 10.1038/eye.2015.120

DO - 10.1038/eye.2015.120

M3 - Article

VL - 29

SP - 1340

EP - 1346

JO - Eye

JF - Eye

SN - 0950-222X

IS - 10

ER -