Delayed vasovasostomy: Experimental study using fibrin glue

O. Vankemmel, J. M. Rigot, T. Burnouf, E. Mazeman

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

We compared delayed vasectomy reversals performed in rats using fibrin glue combined with 3 transmural sutures or a conventional microsurgical technique. Forty Sprague-Dawley rats underwent bilateral vasectomy followed 2 weeks later by bilateral vasovasostomy using fibrin glue or a conventional microsurgical suture technique. Our protocol evaluated fertility rates after a 3-week mating period, sperm granuloma formation, histological changes at the anastomotic site, longitudinal tensile strength and mean testicular weight. The fibrin glue technique required significantly reduced operative time (p <0.0005) and showed statistically lower tensile strength performance (p <0.0005). All other parameters showed no statistical difference between the two techniques. Fibrin-glued vasovasostomy is efficient in a delayed protocol and deserves further clinical experience.

Original languageEnglish
Pages (from-to)182-186
Number of pages5
JournalEuropean Urology
Volume31
Issue number2
Publication statusPublished - 1997
Externally publishedYes

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Keywords

  • Fibrin adhesive
  • Microsurgery
  • Vasectomy reversal

ASJC Scopus subject areas

  • Urology

Cite this

Vankemmel, O., Rigot, J. M., Burnouf, T., & Mazeman, E. (1997). Delayed vasovasostomy: Experimental study using fibrin glue. European Urology, 31(2), 182-186.