Deformity of duodenal bulb, gastric metaplasia of duodenal regenerating mucosa and recurrence of duodenal ulcer: A correlated study

Chun Chao Chang, Shiann Pan, Gi Shih Lien, Cheng Hsiung Liao, Sheng-Hsuan Chen, Yeong-Shan Cheng

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Aim: To investigate the correlation among the presence and degree of gastric metaplasia of duodenal regenerating mucosa, the deformity of bulb and the recurrence of duodenal ulcer. Methods: A total of 99 patients with duodenal ulcer were treated with H2-antagonist with or without antimicrobial therapy. All patients received follow-up endoscopic examinations 6 wk after treatment. When the ulcer(s) were noted to be healed, two biopsies were taken from the ulcer scar for histological study of gastric metaplasia, and 4 biopsies were taken from antrum for Helicobacter pylori (H pylori) study. Out of these cases, 44 received further follow-up endoscopic examinations after 3, 6 and 12 mo respectively for studying the recurrence rate of duodenal ulcers. The correlation among ulcer recurrence, degree of gastric metaplasia of regenerating mucosa, bulbar deformity, and colonization of H pylori in the stomach was then studied. Results: The results showed that there was a strong correlation between the deformity of duodenal bulb and the degree of gastric metaplasia of regenerating duodenal mucosa. The recurrence rate of duodenal ulcer had a significant difference between patients with and without H pylori colonization in the stomach (P

Original languageEnglish
Pages (from-to)1802-1805
Number of pages4
JournalWorld Journal of Gastroenterology
Volume11
Issue number12
Publication statusPublished - Mar 28 2005

Keywords

  • Dluodenal regeneration
  • Gastric metaplasia

ASJC Scopus subject areas

  • Gastroenterology

Fingerprint Dive into the research topics of 'Deformity of duodenal bulb, gastric metaplasia of duodenal regenerating mucosa and recurrence of duodenal ulcer: A correlated study'. Together they form a unique fingerprint.

  • Cite this