Decreased Retinol Binding Protein 4 Concentrations are Associated With Cholesterol Gallstone Disease

Shen Nien Wang; Yao Tsung Yeh; Sen Teh Wang; Yi Ling Chen; Shih Chang Chuang; Chen Guo Ker; King Teh Lee

doi:10.1016/S0929-6646(10)60073-3

Decreased Retinol Binding Protein 4 Concentrations are Associated With Cholesterol Gallstone Disease

Shen Nien Wang, Yao Tsung Yeh, Sen Teh Wang, Yi Ling Chen, Shih Chang Chuang, Chen Guo Ker, King Teh Lee

Research output: Contribution to journal › Article

6 Citations (Scopus)

Abstract

Background/Purpose: Circulating retinol binding protein 4 (RBP4) is associated with a variety of obesity-related diseases. This study investigated whether there were aberrant concentrations of RBP4 in cholesterol gallstone disease. Methods: Serum RBP4 levels of 100 cholesterol gallstone patients and 147 healthy controls were measured by enzyme-linked immunosorbent assay and further correlated with clinical and biochemical characteristics, including insulin resistance and renal function. Gallstone specimens were obtained during laparoscopic cholecystectomy and analyzed for their chemical composition using Fourier transform infrared spectroscopy. Results: Significantly lower serum RBP4 levels were found in patients with cholesterol gallstones in comparison with controls (30.57 ± 13.64 mg/L vs. 41.52 ± 20.25 mg/L, p

Original language	English
Pages (from-to)	422-429
Number of pages	8
Journal	Journal of the Formosan Medical Association = Taiwan yi zhi
Volume	109
Issue number	6
DOIs	https://doi.org/10.1016/S0929-6646(10)60073-3
Publication status	Published - Jun 2010

Keywords

adipokine
cholesterol gallstone
insulin resistance
renal function
retinol binding protein 4

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1016/S0929-6646(10)60073-3

Fingerprint Dive into the research topics of 'Decreased Retinol Binding Protein 4 Concentrations are Associated With Cholesterol Gallstone Disease'. Together they form a unique fingerprint.

Cite this

Wang, S. N., Yeh, Y. T., Wang, S. T., Chen, Y. L., Chuang, S. C., Ker, C. G., & Lee, K. T. (2010). Decreased Retinol Binding Protein 4 Concentrations are Associated With Cholesterol Gallstone Disease. Journal of the Formosan Medical Association = Taiwan yi zhi, 109(6), 422-429. https://doi.org/10.1016/S0929-6646(10)60073-3

Decreased Retinol Binding Protein 4 Concentrations are Associated With Cholesterol Gallstone Disease. / Wang, Shen Nien; Yeh, Yao Tsung; Wang, Sen Teh; Chen, Yi Ling; Chuang, Shih Chang; Ker, Chen Guo; Lee, King Teh.

In: Journal of the Formosan Medical Association = Taiwan yi zhi, Vol. 109, No. 6, 06.2010, p. 422-429.

Research output: Contribution to journal › Article

@article{85d949268ec347aab587eefad7ef7c6e,

title = "Decreased Retinol Binding Protein 4 Concentrations are Associated With Cholesterol Gallstone Disease",

abstract = "Background/Purpose: Circulating retinol binding protein 4 (RBP4) is associated with a variety of obesity-related diseases. This study investigated whether there were aberrant concentrations of RBP4 in cholesterol gallstone disease. Methods: Serum RBP4 levels of 100 cholesterol gallstone patients and 147 healthy controls were measured by enzyme-linked immunosorbent assay and further correlated with clinical and biochemical characteristics, including insulin resistance and renal function. Gallstone specimens were obtained during laparoscopic cholecystectomy and analyzed for their chemical composition using Fourier transform infrared spectroscopy. Results: Significantly lower serum RBP4 levels were found in patients with cholesterol gallstones in comparison with controls (30.57 ± 13.64 mg/L vs. 41.52 ± 20.25 mg/L, p",

keywords = "adipokine, cholesterol gallstone, insulin resistance, renal function, retinol binding protein 4",

author = "Wang, {Shen Nien} and Yeh, {Yao Tsung} and Wang, {Sen Teh} and Chen, {Yi Ling} and Chuang, {Shih Chang} and Ker, {Chen Guo} and Lee, {King Teh}",

year = "2010",

month = jun,

doi = "10.1016/S0929-6646(10)60073-3",

language = "English",

volume = "109",

pages = "422--429",

journal = "Journal of the Formosan Medical Association",

issn = "0929-6646",

publisher = "Elsevier Science Publishers B.V.",

number = "6",

}

TY - JOUR

T1 - Decreased Retinol Binding Protein 4 Concentrations are Associated With Cholesterol Gallstone Disease

AU - Wang, Shen Nien

AU - Yeh, Yao Tsung

AU - Wang, Sen Teh

AU - Chen, Yi Ling

AU - Chuang, Shih Chang

AU - Ker, Chen Guo

AU - Lee, King Teh

PY - 2010/6

Y1 - 2010/6

N2 - Background/Purpose: Circulating retinol binding protein 4 (RBP4) is associated with a variety of obesity-related diseases. This study investigated whether there were aberrant concentrations of RBP4 in cholesterol gallstone disease. Methods: Serum RBP4 levels of 100 cholesterol gallstone patients and 147 healthy controls were measured by enzyme-linked immunosorbent assay and further correlated with clinical and biochemical characteristics, including insulin resistance and renal function. Gallstone specimens were obtained during laparoscopic cholecystectomy and analyzed for their chemical composition using Fourier transform infrared spectroscopy. Results: Significantly lower serum RBP4 levels were found in patients with cholesterol gallstones in comparison with controls (30.57 ± 13.64 mg/L vs. 41.52 ± 20.25 mg/L, p

AB - Background/Purpose: Circulating retinol binding protein 4 (RBP4) is associated with a variety of obesity-related diseases. This study investigated whether there were aberrant concentrations of RBP4 in cholesterol gallstone disease. Methods: Serum RBP4 levels of 100 cholesterol gallstone patients and 147 healthy controls were measured by enzyme-linked immunosorbent assay and further correlated with clinical and biochemical characteristics, including insulin resistance and renal function. Gallstone specimens were obtained during laparoscopic cholecystectomy and analyzed for their chemical composition using Fourier transform infrared spectroscopy. Results: Significantly lower serum RBP4 levels were found in patients with cholesterol gallstones in comparison with controls (30.57 ± 13.64 mg/L vs. 41.52 ± 20.25 mg/L, p

KW - adipokine

KW - cholesterol gallstone

KW - insulin resistance

KW - renal function

KW - retinol binding protein 4

UR - http://www.scopus.com/inward/record.url?scp=77953671231&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77953671231&partnerID=8YFLogxK

U2 - 10.1016/S0929-6646(10)60073-3

DO - 10.1016/S0929-6646(10)60073-3

M3 - Article

C2 - 20610143

AN - SCOPUS:77953671231

VL - 109

SP - 422

EP - 429

JO - Journal of the Formosan Medical Association

JF - Journal of the Formosan Medical Association

SN - 0929-6646

IS - 6

ER -