Data supporting the angiotensin II activates MEL18 to deSUMOylate HSF2 for hypertension-related heart failure

Chih Yang Huang, Chia Hua Kuo, Pei Ying Pai, Tsung Jung Ho, Yueh Min Lin, Ray Jade Chen, Fuu Jen Tsai, V. Vijaya Padma, Wei Wen Kuo, Chih Yang Huang

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

In association with the published article “Inhibition of HSF2 SUMOylation via MEL18 upregulates IGF-IIR and leads to hypertension-induced cardiac hypertrophy” (Huang et al., 2017) [1], this data article contains information about deSUMOylation of HSF2 on lysine 82 on angiotensin II (ANG II) -induced cardiac hypertrophy, which is mediated by MEL18. Isolated adult human whole heart tissue showed MEL18-mediated HSF2-IGF-IIR pathway is upregulated in hypertension human heart, compared to health human heart.

Original languageEnglish
Pages (from-to)521-526
Number of pages6
JournalData in Brief
Volume16
DOIs
Publication statusPublished - Feb 1 2018

ASJC Scopus subject areas

  • General

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