Cytogenetic studies of lymphoma cells from an american patient with a tumor similar to burkitt's tumors in african children

Elizabeth W. Chu, Jacqueline J.K. Whang, Alan S. Rabson

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Cytogenetic studies were done on lymphoma cells from ascitic fluid of an American woman with a tumor similar to Burkitt's tumors in African children and on the established cell culture line (AL-2) derived from the ascites cells, More than 90% of the metaphases in direct preparations of the ascitic fluid contained an extra submedium chromosome, larger than pair #1, and lacked one chromosome from this #1 pair. The AL-2 line had a chromosome number distribution ranging from 42–86 with a modal number of 46, and the cells with 46 chromosomes had an apparently normal female karyotype. None of the AL-2 cells showed any marker chromosomes. The cultural conditions apparently favored the growth of those cells without the marker chromosome.

Original languageEnglish
Pages (from-to)885-891
Number of pages7
JournalJournal of the National Cancer Institute
Volume37
Issue number6
DOIs
Publication statusPublished - Jan 1 1966
Externally publishedYes

Fingerprint

Burkitt Lymphoma
Cytogenetics
Lymphoma
Chromosomes
Ascitic Fluid
Genetic Markers
Neoplasms
Chromosomes, Human, Pair 1
Metaphase
Karyotype
Ascites
Cell Culture Techniques
Cell Count
Cell Line
Growth

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Cytogenetic studies of lymphoma cells from an american patient with a tumor similar to burkitt's tumors in african children. / Chu, Elizabeth W.; Whang, Jacqueline J.K.; Rabson, Alan S.

In: Journal of the National Cancer Institute, Vol. 37, No. 6, 01.01.1966, p. 885-891.

Research output: Contribution to journalArticle

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