Current controversies: Sinus disease and the lower airways

Ching Tzao, Peter A. Nickerson, James A. Russell, Sylvia F. Gugino, Robin H. Steinhorn

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

This review explores the literature dealing with the relation between the upper and lower airways, including the possible link between chronic sinus disease and asthma, and between chronic sinus disease and cough. Imaging studies, microbiology, epidemiology, animal studies, and effects of treatment are discussed. Available studies do not prove that upper airway disease directly causes lower airway pathology. Allergic rhinitis causing nasal blockage needs treatment, as does symptomatic sinus disease. Where there is concurrent disease of the upper and lower airways, both conditions need to be treated adequately. Further research is required to establish the relation between upper and lower airways, and animal models may help to unravel the mechanisms and impact of treatment. Randomized, blinded, controlled trials are needed in both children and adults to assess therapies of chronic sinusitis and the response of asthma.

Original languageEnglish
Pages (from-to)165-172
Number of pages8
JournalPediatric Pulmonology
Volume31
Issue number2
DOIs
Publication statusPublished - 2001
Externally publishedYes

Fingerprint

Chronic Disease
Asthma
Nasal Obstruction
Sinusitis
Therapeutics
Microbiology
Cough
Epidemiology
Randomized Controlled Trials
Animal Models
Pathology
Research
Allergic Rhinitis

Keywords

  • Airways
  • Asthma
  • Children
  • Cough
  • Sinusitis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine

Cite this

Current controversies : Sinus disease and the lower airways. / Tzao, Ching; Nickerson, Peter A.; Russell, James A.; Gugino, Sylvia F.; Steinhorn, Robin H.

In: Pediatric Pulmonology, Vol. 31, No. 2, 2001, p. 165-172.

Research output: Contribution to journalArticle

Tzao, Ching ; Nickerson, Peter A. ; Russell, James A. ; Gugino, Sylvia F. ; Steinhorn, Robin H. / Current controversies : Sinus disease and the lower airways. In: Pediatric Pulmonology. 2001 ; Vol. 31, No. 2. pp. 165-172.
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