Cryogen spray cooling for spatially selective photocoagulation: a feasibility study with potential application for treatment of hemangiomas

Bahman Anvari, B. S. Tanenbaum, Thomas E. Milner, Wendy Hoffman, Samireh Said, Cheng Jen Chang, Lih Hueh L. Liaw, Sol Kimel, John S.M.D. Nelson

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

The clinical objective in laser treatment of hemangiomas is to photocoagulate the dilated cutaneous blood vessels, while at the same time minimizing nonspecific thermal injury to the overlying epidermis. We present an in-vivo experimental procedure, using a chicken comb animal model, and an infrared feedback system to deliver repetitive cryogen spurts during continuous Nd:YAG laser irradiation. Gross and histologic observations are consistent with calculated thicknesses of protected and damaged tissues, and demonstrate the feasibility of inducing spatially selective photocoagulation when using cryogen spray cooling in conjunction with laser irradiation. Experimental observation of epidermal protection in the chicken comb model suggests selective photocoagulation of subsurface targeted blood vessels for successful treatment of hemangiomas can be achieved by repetitive applications of a cryogen spurt during continuous Nd:YAG laser irradiation.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsFrederic Laffitte, Raimund Hibst, Hans-Dieter Reidenbach, Herbert J. Geschwind, Giulio Maira, et.al.
Pages29-37
Number of pages9
Volume2922
Publication statusPublished - Dec 1 1996
Externally publishedYes
EventLaser Applications in Medicine and Dentistry - Vienna, Austria
Duration: Sep 7 1996Sep 10 1996

Conference

ConferenceLaser Applications in Medicine and Dentistry
CityVienna, Austria
Period9/7/969/10/96

Fingerprint

Spray
Laser beam effects
Irradiation
sprayers
Cooling
chickens
Nd:YAG Laser
Blood Vessels
blood vessels
Blood vessels
cooling
irradiation
YAG lasers
Laser
epidermis
Animal Model
Epidermis
animal models
Feedback Systems
Gross

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Cite this

Anvari, B., Tanenbaum, B. S., Milner, T. E., Hoffman, W., Said, S., Chang, C. J., ... Nelson, J. S. M. D. (1996). Cryogen spray cooling for spatially selective photocoagulation: a feasibility study with potential application for treatment of hemangiomas. In F. Laffitte, R. Hibst, H-D. Reidenbach, H. J. Geschwind, G. Maira, & et.al. (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 2922, pp. 29-37)

Cryogen spray cooling for spatially selective photocoagulation : a feasibility study with potential application for treatment of hemangiomas. / Anvari, Bahman; Tanenbaum, B. S.; Milner, Thomas E.; Hoffman, Wendy; Said, Samireh; Chang, Cheng Jen; Liaw, Lih Hueh L.; Kimel, Sol; Nelson, John S.M.D.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / Frederic Laffitte; Raimund Hibst; Hans-Dieter Reidenbach; Herbert J. Geschwind; Giulio Maira; et.al. Vol. 2922 1996. p. 29-37.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Anvari, B, Tanenbaum, BS, Milner, TE, Hoffman, W, Said, S, Chang, CJ, Liaw, LHL, Kimel, S & Nelson, JSMD 1996, Cryogen spray cooling for spatially selective photocoagulation: a feasibility study with potential application for treatment of hemangiomas. in F Laffitte, R Hibst, H-D Reidenbach, HJ Geschwind, G Maira & et.al. (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 2922, pp. 29-37, Laser Applications in Medicine and Dentistry, Vienna, Austria, 9/7/96.
Anvari B, Tanenbaum BS, Milner TE, Hoffman W, Said S, Chang CJ et al. Cryogen spray cooling for spatially selective photocoagulation: a feasibility study with potential application for treatment of hemangiomas. In Laffitte F, Hibst R, Reidenbach H-D, Geschwind HJ, Maira G, et.al., editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 2922. 1996. p. 29-37
Anvari, Bahman ; Tanenbaum, B. S. ; Milner, Thomas E. ; Hoffman, Wendy ; Said, Samireh ; Chang, Cheng Jen ; Liaw, Lih Hueh L. ; Kimel, Sol ; Nelson, John S.M.D. / Cryogen spray cooling for spatially selective photocoagulation : a feasibility study with potential application for treatment of hemangiomas. Proceedings of SPIE - The International Society for Optical Engineering. editor / Frederic Laffitte ; Raimund Hibst ; Hans-Dieter Reidenbach ; Herbert J. Geschwind ; Giulio Maira ; et.al. Vol. 2922 1996. pp. 29-37
@inproceedings{bd4f4730f45c4ff69edecd52dac666f6,
title = "Cryogen spray cooling for spatially selective photocoagulation: a feasibility study with potential application for treatment of hemangiomas",
abstract = "The clinical objective in laser treatment of hemangiomas is to photocoagulate the dilated cutaneous blood vessels, while at the same time minimizing nonspecific thermal injury to the overlying epidermis. We present an in-vivo experimental procedure, using a chicken comb animal model, and an infrared feedback system to deliver repetitive cryogen spurts during continuous Nd:YAG laser irradiation. Gross and histologic observations are consistent with calculated thicknesses of protected and damaged tissues, and demonstrate the feasibility of inducing spatially selective photocoagulation when using cryogen spray cooling in conjunction with laser irradiation. Experimental observation of epidermal protection in the chicken comb model suggests selective photocoagulation of subsurface targeted blood vessels for successful treatment of hemangiomas can be achieved by repetitive applications of a cryogen spurt during continuous Nd:YAG laser irradiation.",
author = "Bahman Anvari and Tanenbaum, {B. S.} and Milner, {Thomas E.} and Wendy Hoffman and Samireh Said and Chang, {Cheng Jen} and Liaw, {Lih Hueh L.} and Sol Kimel and Nelson, {John S.M.D.}",
year = "1996",
month = "12",
day = "1",
language = "English",
isbn = "0819423246",
volume = "2922",
pages = "29--37",
editor = "Frederic Laffitte and Raimund Hibst and Hans-Dieter Reidenbach and Geschwind, {Herbert J.} and Giulio Maira and et.al.",
booktitle = "Proceedings of SPIE - The International Society for Optical Engineering",

}

TY - GEN

T1 - Cryogen spray cooling for spatially selective photocoagulation

T2 - a feasibility study with potential application for treatment of hemangiomas

AU - Anvari, Bahman

AU - Tanenbaum, B. S.

AU - Milner, Thomas E.

AU - Hoffman, Wendy

AU - Said, Samireh

AU - Chang, Cheng Jen

AU - Liaw, Lih Hueh L.

AU - Kimel, Sol

AU - Nelson, John S.M.D.

PY - 1996/12/1

Y1 - 1996/12/1

N2 - The clinical objective in laser treatment of hemangiomas is to photocoagulate the dilated cutaneous blood vessels, while at the same time minimizing nonspecific thermal injury to the overlying epidermis. We present an in-vivo experimental procedure, using a chicken comb animal model, and an infrared feedback system to deliver repetitive cryogen spurts during continuous Nd:YAG laser irradiation. Gross and histologic observations are consistent with calculated thicknesses of protected and damaged tissues, and demonstrate the feasibility of inducing spatially selective photocoagulation when using cryogen spray cooling in conjunction with laser irradiation. Experimental observation of epidermal protection in the chicken comb model suggests selective photocoagulation of subsurface targeted blood vessels for successful treatment of hemangiomas can be achieved by repetitive applications of a cryogen spurt during continuous Nd:YAG laser irradiation.

AB - The clinical objective in laser treatment of hemangiomas is to photocoagulate the dilated cutaneous blood vessels, while at the same time minimizing nonspecific thermal injury to the overlying epidermis. We present an in-vivo experimental procedure, using a chicken comb animal model, and an infrared feedback system to deliver repetitive cryogen spurts during continuous Nd:YAG laser irradiation. Gross and histologic observations are consistent with calculated thicknesses of protected and damaged tissues, and demonstrate the feasibility of inducing spatially selective photocoagulation when using cryogen spray cooling in conjunction with laser irradiation. Experimental observation of epidermal protection in the chicken comb model suggests selective photocoagulation of subsurface targeted blood vessels for successful treatment of hemangiomas can be achieved by repetitive applications of a cryogen spurt during continuous Nd:YAG laser irradiation.

UR - http://www.scopus.com/inward/record.url?scp=0030359060&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030359060&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:0030359060

SN - 0819423246

SN - 9780819423245

VL - 2922

SP - 29

EP - 37

BT - Proceedings of SPIE - The International Society for Optical Engineering

A2 - Laffitte, Frederic

A2 - Hibst, Raimund

A2 - Reidenbach, Hans-Dieter

A2 - Geschwind, Herbert J.

A2 - Maira, Giulio

A2 - et.al., null

ER -