Creation of a reflecting formula to determine a patient's indication for undergoing total knee arthroplasty

Wing P. Chan, Shu Mei Hsu, Guo Shu Huang, Min Szu Yao, Yue Chune Chang, Wei-Pin Ho

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: The aim of this study was to develop, from patients' characteristics and radiography, a formula reflecting the decision for total knee arthroplasty (TKA) in patients with a painful osteoarthritic knee. Methods: We reviewed medical records of 193 consecutive patients who had knee osteoarthritis and underwent primary TKA surgery and 133 consecutive patients with knee osteoarthritis who did not have surgery in one institution during the preceding 5 years. Two skeletal radiologists graded, from 0 to 3, radiographic joint space narrowing (JSN), osteophytes, subchondral sclerosis, and subchondral cysts. The association between the variables and outcome were calculated by the chi-squared test and multivariable logistic regression. Results: Women had more TKAs than men (P = 0.002), and the TKA and non-TKA groups differed in terms of self-care ability (P <0.001). There were no significant differences in age or body mass index between the two groups. The relevant factors in the reflective formula were age, sex, self-care ability, JSN, and osteophytes in the medial compartment. The retrospective sensitivity and specificity for patients who underwent TKA surgery were 84% and 83%, respectively. The diagnostic efficacy in retrospect evaluated by a receiver operating characteristic curve was 0.92. Conclusions: A formula reflecting the decision for TKA surgery in patients with a painful osteoarthritic knee has been developed with acceptable diagnostic efficacy obtained retrospectively. The formula should be validated by further study.

Original languageEnglish
Pages (from-to)44-50
Number of pages7
JournalJournal of Orthopaedic Science
Volume15
Issue number1
DOIs
Publication statusPublished - Jan 2010

Fingerprint

Knee Replacement Arthroplasties
Osteophyte
Knee Osteoarthritis
Self Care
Knee
Joints
Bone Cysts
Sclerosis
Radiography
ROC Curve
Medical Records
Body Mass Index
Logistic Models
Sensitivity and Specificity

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

Cite this

Creation of a reflecting formula to determine a patient's indication for undergoing total knee arthroplasty. / Chan, Wing P.; Hsu, Shu Mei; Huang, Guo Shu; Yao, Min Szu; Chang, Yue Chune; Ho, Wei-Pin.

In: Journal of Orthopaedic Science, Vol. 15, No. 1, 01.2010, p. 44-50.

Research output: Contribution to journalArticle

Chan, Wing P. ; Hsu, Shu Mei ; Huang, Guo Shu ; Yao, Min Szu ; Chang, Yue Chune ; Ho, Wei-Pin. / Creation of a reflecting formula to determine a patient's indication for undergoing total knee arthroplasty. In: Journal of Orthopaedic Science. 2010 ; Vol. 15, No. 1. pp. 44-50.
@article{9e48727d4b9f4ba09e75e6c818c169c5,
title = "Creation of a reflecting formula to determine a patient's indication for undergoing total knee arthroplasty",
abstract = "Background: The aim of this study was to develop, from patients' characteristics and radiography, a formula reflecting the decision for total knee arthroplasty (TKA) in patients with a painful osteoarthritic knee. Methods: We reviewed medical records of 193 consecutive patients who had knee osteoarthritis and underwent primary TKA surgery and 133 consecutive patients with knee osteoarthritis who did not have surgery in one institution during the preceding 5 years. Two skeletal radiologists graded, from 0 to 3, radiographic joint space narrowing (JSN), osteophytes, subchondral sclerosis, and subchondral cysts. The association between the variables and outcome were calculated by the chi-squared test and multivariable logistic regression. Results: Women had more TKAs than men (P = 0.002), and the TKA and non-TKA groups differed in terms of self-care ability (P <0.001). There were no significant differences in age or body mass index between the two groups. The relevant factors in the reflective formula were age, sex, self-care ability, JSN, and osteophytes in the medial compartment. The retrospective sensitivity and specificity for patients who underwent TKA surgery were 84{\%} and 83{\%}, respectively. The diagnostic efficacy in retrospect evaluated by a receiver operating characteristic curve was 0.92. Conclusions: A formula reflecting the decision for TKA surgery in patients with a painful osteoarthritic knee has been developed with acceptable diagnostic efficacy obtained retrospectively. The formula should be validated by further study.",
author = "Chan, {Wing P.} and Hsu, {Shu Mei} and Huang, {Guo Shu} and Yao, {Min Szu} and Chang, {Yue Chune} and Wei-Pin Ho",
year = "2010",
month = "1",
doi = "10.1007/s00776-009-1418-8",
language = "English",
volume = "15",
pages = "44--50",
journal = "Journal of Orthopaedic Science",
issn = "0949-2658",
publisher = "Springer Japan",
number = "1",

}

TY - JOUR

T1 - Creation of a reflecting formula to determine a patient's indication for undergoing total knee arthroplasty

AU - Chan, Wing P.

AU - Hsu, Shu Mei

AU - Huang, Guo Shu

AU - Yao, Min Szu

AU - Chang, Yue Chune

AU - Ho, Wei-Pin

PY - 2010/1

Y1 - 2010/1

N2 - Background: The aim of this study was to develop, from patients' characteristics and radiography, a formula reflecting the decision for total knee arthroplasty (TKA) in patients with a painful osteoarthritic knee. Methods: We reviewed medical records of 193 consecutive patients who had knee osteoarthritis and underwent primary TKA surgery and 133 consecutive patients with knee osteoarthritis who did not have surgery in one institution during the preceding 5 years. Two skeletal radiologists graded, from 0 to 3, radiographic joint space narrowing (JSN), osteophytes, subchondral sclerosis, and subchondral cysts. The association between the variables and outcome were calculated by the chi-squared test and multivariable logistic regression. Results: Women had more TKAs than men (P = 0.002), and the TKA and non-TKA groups differed in terms of self-care ability (P <0.001). There were no significant differences in age or body mass index between the two groups. The relevant factors in the reflective formula were age, sex, self-care ability, JSN, and osteophytes in the medial compartment. The retrospective sensitivity and specificity for patients who underwent TKA surgery were 84% and 83%, respectively. The diagnostic efficacy in retrospect evaluated by a receiver operating characteristic curve was 0.92. Conclusions: A formula reflecting the decision for TKA surgery in patients with a painful osteoarthritic knee has been developed with acceptable diagnostic efficacy obtained retrospectively. The formula should be validated by further study.

AB - Background: The aim of this study was to develop, from patients' characteristics and radiography, a formula reflecting the decision for total knee arthroplasty (TKA) in patients with a painful osteoarthritic knee. Methods: We reviewed medical records of 193 consecutive patients who had knee osteoarthritis and underwent primary TKA surgery and 133 consecutive patients with knee osteoarthritis who did not have surgery in one institution during the preceding 5 years. Two skeletal radiologists graded, from 0 to 3, radiographic joint space narrowing (JSN), osteophytes, subchondral sclerosis, and subchondral cysts. The association between the variables and outcome were calculated by the chi-squared test and multivariable logistic regression. Results: Women had more TKAs than men (P = 0.002), and the TKA and non-TKA groups differed in terms of self-care ability (P <0.001). There were no significant differences in age or body mass index between the two groups. The relevant factors in the reflective formula were age, sex, self-care ability, JSN, and osteophytes in the medial compartment. The retrospective sensitivity and specificity for patients who underwent TKA surgery were 84% and 83%, respectively. The diagnostic efficacy in retrospect evaluated by a receiver operating characteristic curve was 0.92. Conclusions: A formula reflecting the decision for TKA surgery in patients with a painful osteoarthritic knee has been developed with acceptable diagnostic efficacy obtained retrospectively. The formula should be validated by further study.

UR - http://www.scopus.com/inward/record.url?scp=77249155786&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77249155786&partnerID=8YFLogxK

U2 - 10.1007/s00776-009-1418-8

DO - 10.1007/s00776-009-1418-8

M3 - Article

C2 - 20151250

AN - SCOPUS:77249155786

VL - 15

SP - 44

EP - 50

JO - Journal of Orthopaedic Science

JF - Journal of Orthopaedic Science

SN - 0949-2658

IS - 1

ER -