Correlations of serum lipids, uric acid, and albumin among mothers, offspring, and siblings in Taipei, Taiwan

Hsing-Hsien Cheng, Shwu Huey Yang, Cheng Chen, Ming Shu Chiang

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The purpose of this study was to investigate the correlations of serum lipids, uric acid, and albumin, among mothers (n = 111), offspring (n = 208), and siblings (n = 57) in Taipei, Taiwan. Analytical items included serum triglyceride, serum total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, uric acid, and albumin. Statistical analysis was performed according to the SAS UNIVARIATE procedure; while regression coefficient, parent-offspring regressions, paired-comparison and heritability were estimated. These results show higher heritabilities of four types of serum lipids, uric acid and albumin between mothers and testers (b(YX)) or siblings (b(ZX)) by parent-offspring regression analysis. Regression coefficients (b(YX)) of six characters were significantly different (p <0.05 - 0.01). Regression coefficients (b(ZX)) for total cholesterol, low-density lipoprotein cholesterol, uric acid, and albumin were significantly different (p <0.05 - 0.01), showing the result of genetic control, because their heritabilities were very high at 0.75 ~ 1.0, 0.77 ~ 1.0, 0.96 ~ 1.0, and 0.48 ~ 0.82, respectively. This study disclosed that the serum lipids of children in Taipei, Taiwan were significantly correlated with that of parents, which may be attributed to the result of genetic control.

Original languageEnglish
Pages (from-to)225-232
Number of pages8
JournalActa Paediatrica Taiwanica
Volume40
Issue number4
Publication statusPublished - Jul 1999

Fingerprint

Uric Acid
Taiwan
Siblings
Albumins
Mothers
Lipids
Serum
LDL Cholesterol
Cholesterol
Matched-Pair Analysis
HDL Cholesterol
Triglycerides
Parents
Regression Analysis

Keywords

  • Heritability
  • Mother
  • Offspring
  • Serum lipids
  • Taipei

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Correlations of serum lipids, uric acid, and albumin among mothers, offspring, and siblings in Taipei, Taiwan. / Cheng, Hsing-Hsien; Yang, Shwu Huey; Chen, Cheng; Chiang, Ming Shu.

In: Acta Paediatrica Taiwanica, Vol. 40, No. 4, 07.1999, p. 225-232.

Research output: Contribution to journalArticle

@article{e13afc5b9f7e4abe9b8af8b6a6d20696,
title = "Correlations of serum lipids, uric acid, and albumin among mothers, offspring, and siblings in Taipei, Taiwan",
abstract = "The purpose of this study was to investigate the correlations of serum lipids, uric acid, and albumin, among mothers (n = 111), offspring (n = 208), and siblings (n = 57) in Taipei, Taiwan. Analytical items included serum triglyceride, serum total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, uric acid, and albumin. Statistical analysis was performed according to the SAS UNIVARIATE procedure; while regression coefficient, parent-offspring regressions, paired-comparison and heritability were estimated. These results show higher heritabilities of four types of serum lipids, uric acid and albumin between mothers and testers (b(YX)) or siblings (b(ZX)) by parent-offspring regression analysis. Regression coefficients (b(YX)) of six characters were significantly different (p <0.05 - 0.01). Regression coefficients (b(ZX)) for total cholesterol, low-density lipoprotein cholesterol, uric acid, and albumin were significantly different (p <0.05 - 0.01), showing the result of genetic control, because their heritabilities were very high at 0.75 ~ 1.0, 0.77 ~ 1.0, 0.96 ~ 1.0, and 0.48 ~ 0.82, respectively. This study disclosed that the serum lipids of children in Taipei, Taiwan were significantly correlated with that of parents, which may be attributed to the result of genetic control.",
keywords = "Heritability, Mother, Offspring, Serum lipids, Taipei",
author = "Hsing-Hsien Cheng and Yang, {Shwu Huey} and Cheng Chen and Chiang, {Ming Shu}",
year = "1999",
month = "7",
language = "English",
volume = "40",
pages = "225--232",
journal = "Pediatrics and Neonatology",
issn = "1875-9572",
publisher = "臺灣兒科醫學會",
number = "4",

}

TY - JOUR

T1 - Correlations of serum lipids, uric acid, and albumin among mothers, offspring, and siblings in Taipei, Taiwan

AU - Cheng, Hsing-Hsien

AU - Yang, Shwu Huey

AU - Chen, Cheng

AU - Chiang, Ming Shu

PY - 1999/7

Y1 - 1999/7

N2 - The purpose of this study was to investigate the correlations of serum lipids, uric acid, and albumin, among mothers (n = 111), offspring (n = 208), and siblings (n = 57) in Taipei, Taiwan. Analytical items included serum triglyceride, serum total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, uric acid, and albumin. Statistical analysis was performed according to the SAS UNIVARIATE procedure; while regression coefficient, parent-offspring regressions, paired-comparison and heritability were estimated. These results show higher heritabilities of four types of serum lipids, uric acid and albumin between mothers and testers (b(YX)) or siblings (b(ZX)) by parent-offspring regression analysis. Regression coefficients (b(YX)) of six characters were significantly different (p <0.05 - 0.01). Regression coefficients (b(ZX)) for total cholesterol, low-density lipoprotein cholesterol, uric acid, and albumin were significantly different (p <0.05 - 0.01), showing the result of genetic control, because their heritabilities were very high at 0.75 ~ 1.0, 0.77 ~ 1.0, 0.96 ~ 1.0, and 0.48 ~ 0.82, respectively. This study disclosed that the serum lipids of children in Taipei, Taiwan were significantly correlated with that of parents, which may be attributed to the result of genetic control.

AB - The purpose of this study was to investigate the correlations of serum lipids, uric acid, and albumin, among mothers (n = 111), offspring (n = 208), and siblings (n = 57) in Taipei, Taiwan. Analytical items included serum triglyceride, serum total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, uric acid, and albumin. Statistical analysis was performed according to the SAS UNIVARIATE procedure; while regression coefficient, parent-offspring regressions, paired-comparison and heritability were estimated. These results show higher heritabilities of four types of serum lipids, uric acid and albumin between mothers and testers (b(YX)) or siblings (b(ZX)) by parent-offspring regression analysis. Regression coefficients (b(YX)) of six characters were significantly different (p <0.05 - 0.01). Regression coefficients (b(ZX)) for total cholesterol, low-density lipoprotein cholesterol, uric acid, and albumin were significantly different (p <0.05 - 0.01), showing the result of genetic control, because their heritabilities were very high at 0.75 ~ 1.0, 0.77 ~ 1.0, 0.96 ~ 1.0, and 0.48 ~ 0.82, respectively. This study disclosed that the serum lipids of children in Taipei, Taiwan were significantly correlated with that of parents, which may be attributed to the result of genetic control.

KW - Heritability

KW - Mother

KW - Offspring

KW - Serum lipids

KW - Taipei

UR - http://www.scopus.com/inward/record.url?scp=0032695343&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032695343&partnerID=8YFLogxK

M3 - Article

C2 - 10910618

AN - SCOPUS:0032695343

VL - 40

SP - 225

EP - 232

JO - Pediatrics and Neonatology

JF - Pediatrics and Neonatology

SN - 1875-9572

IS - 4

ER -