Corpus callosotomy in a patient of hemimegalencephaly and Lennox-Gastaut syndrome

Shang Yeong Kwan, Hann Yeh Shyu, Ji Ho Lin, Tai-Tong Wong, Kai Ping Chang, Chun Hing Yiu

Research output: Contribution to journalArticle

Abstract

We report the case of a girl with hemimegalencephaly (HME) and Lennox-Gastaut syndrome (LGS) treated by callosotomy at 1 year of age. Over 10 years, her seizure frequency and severity decreased markedly. Hemispherectomy is the main surgical option for HME although HME appears to correlate with a less favorable seizure outcome. However, the clinical presentation of LGS and possible generalized cortical dysplasia, which is indicative of a secondarily generalized epilepsy, might predict a favorable surgical outcome of corpus callosotomy in patients of HME, as in our case.

Original languageEnglish
Pages (from-to)643-646
Number of pages4
JournalBrain and Development
Volume30
Issue number10
DOIs
Publication statusPublished - Nov 1 2008
Externally publishedYes

Fingerprint

Seizures
Hemispherectomy
Malformations of Cortical Development
Generalized Epilepsy
Hemimegalencephaly
Lennox Gastaut Syndrome

Keywords

  • Corpus callosotomy
  • Epilepsy
  • Generalized cortical dysplasia
  • Hemimegalencephaly
  • Lennox-Gastaut syndrome

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Clinical Neurology

Cite this

Corpus callosotomy in a patient of hemimegalencephaly and Lennox-Gastaut syndrome. / Kwan, Shang Yeong; Shyu, Hann Yeh; Lin, Ji Ho; Wong, Tai-Tong; Chang, Kai Ping; Yiu, Chun Hing.

In: Brain and Development, Vol. 30, No. 10, 01.11.2008, p. 643-646.

Research output: Contribution to journalArticle

Kwan, Shang Yeong ; Shyu, Hann Yeh ; Lin, Ji Ho ; Wong, Tai-Tong ; Chang, Kai Ping ; Yiu, Chun Hing. / Corpus callosotomy in a patient of hemimegalencephaly and Lennox-Gastaut syndrome. In: Brain and Development. 2008 ; Vol. 30, No. 10. pp. 643-646.
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