Coronary artery disease in dialysis patients: What is the optimal therapy?

Research output: Contribution to journalArticle

Abstract

Coronary artery disease (CAD) carries a high risk of mortality in dialysis patients. End-stage renal disease is considered to increase the vulnerability of patients with atherosclerosis superimposed on artery calcification. Recently, an increasing prevalence of CAD in dialysis patients has been attributed to a lack of effective prevention and treatment. Further studies have shown that optimal therapies for CAD in dialysis patients remain neglected and unclarified. These therapies include correction of anemia, control of blood pressure, and antiplatelet therapy. Because of bleeding tendencies in dialysis patients, the benefits of antiplatelet therapy and platelet glycoprotein IIb/IIIa inhibitors for treating CAD require more research. In addition, a meta-analysis of retrospective studies in 2012 showed that dialysis patients with CAD receiving coronary artery bypass surgery had a lower long-term mortality rate and fewer postoperative cardiac complications than those receiving percutaneous coronary angioplasty. A large randomized, long-term cohort study is necessary to confirm these issues.

Original languageEnglish
Pages (from-to)82-85
Number of pages4
JournalTzu Chi Medical Journal
Volume25
Issue number2
DOIs
Publication statusPublished - Jun 2013

Fingerprint

Coronary Artery Disease
Dialysis
Therapeutics
Integrin beta3
Platelet Glycoprotein GPIIb-IIIa Complex
Mortality
Angioplasty
Coronary Artery Bypass
Chronic Kidney Failure
Meta-Analysis
Anemia
Atherosclerosis
Cohort Studies
Retrospective Studies
Arteries
Hemorrhage
Blood Pressure
Research

Keywords

  • Coronary artery bypass grafting
  • Coronary artery disease
  • Dialysis
  • Percutaneous transluminal coronary angioplasty
  • Stent

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Coronary artery disease in dialysis patients : What is the optimal therapy? / Chou, Chu Lin; Fang, Te Chao.

In: Tzu Chi Medical Journal, Vol. 25, No. 2, 06.2013, p. 82-85.

Research output: Contribution to journalArticle

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