Continuous production of dicarboxylic acid by immobilized Pseudomonas aeruginosa cells

Err Cheng Chan, Chin Sheng Cheng, Yuan Hsun Hsu

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Treatment of Pseudomonas aeruginosa with 3% (v/v) Tween 80 resulted in a 16-fold increase in the yield of conversion of n-pentadecane to the corresponding dioic acid, tridecane 1,13-dicarboxylic acid (DC-15). However, this conversion process was inhibited by high concentrations of DC-15. To avoid this product inhibition, a continuous process with immobilized cells was performed, and the results showed that the DC-15 yield was four-fold higher than in the case of batch type DC-15 production. The continuous process used in this study is adaptable to large-scale production of DC-15.

Original languageEnglish
Pages (from-to)157-160
Number of pages4
JournalJournal of Fermentation and Bioengineering
Volume83
Issue number2
DOIs
Publication statusPublished - 1997

Fingerprint

Immobilized Cells
Dicarboxylic Acids
Polysorbates
Pseudomonas aeruginosa
Acids
Cells
tridecane
pentadecane

Keywords

  • 1,13-dicarboxylic acid
  • bioconversion
  • Pseudomonas aeruginosa

ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology

Cite this

Continuous production of dicarboxylic acid by immobilized Pseudomonas aeruginosa cells. / Chan, Err Cheng; Cheng, Chin Sheng; Hsu, Yuan Hsun.

In: Journal of Fermentation and Bioengineering, Vol. 83, No. 2, 1997, p. 157-160.

Research output: Contribution to journalArticle

Chan, Err Cheng ; Cheng, Chin Sheng ; Hsu, Yuan Hsun. / Continuous production of dicarboxylic acid by immobilized Pseudomonas aeruginosa cells. In: Journal of Fermentation and Bioengineering. 1997 ; Vol. 83, No. 2. pp. 157-160.
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