Congenital cerebral primitive neuroectodermal tumor with astrocytic differentiation and extracranial metastases

I. Ting Yu; Donald M. Ho; Tai-Tong Wong; Hung Chang Liu

doi:10.1007/BF00308497

Congenital cerebral primitive neuroectodermal tumor with astrocytic differentiation and extracranial metastases

I. Ting Yu, Donald M. Ho, Tai-Tong Wong, Hung Chang Liu

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

A cerebral primitive neuroectodermal tumor with astrocytic differentiation and extracranial metastases in a 28-day-old infant is reported. The infant presented with a progressively enlarged head, cutaneous lesions in the neck, and enlarged cervical lymph nodes. A computed tomography brain scan demonstrated a giant thalamic tumor with subarachnoid dissemination and hydrocephalus. Biopsy material from the cervical lesions showed a picture of glioma with anaplastic astrocytes. The patient received a ventriculoperitoneal shunt operation and palliative chemotherapy, but died at 3 months of age. Autopsy was performed. Histological studies, which included immunohistochemical stains of the thalamic tumor, showed small, round, primitive, neoplastic cells with focal astrocytic differentiation.

Original language	English
Pages (from-to)	179-182
Number of pages	4
Journal	Child's Nervous System
Volume	6
Issue number	3
DOIs	https://doi.org/10.1007/BF00308497
Publication status	Published - May 1 1990
Externally published	Yes

Keywords

Astròcytic differentiation
Extracranial metastases
Primitive neuroectodermal tumor

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Clinical Neurology

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10.1007/BF00308497

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Cite this

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abstract = "A cerebral primitive neuroectodermal tumor with astrocytic differentiation and extracranial metastases in a 28-day-old infant is reported. The infant presented with a progressively enlarged head, cutaneous lesions in the neck, and enlarged cervical lymph nodes. A computed tomography brain scan demonstrated a giant thalamic tumor with subarachnoid dissemination and hydrocephalus. Biopsy material from the cervical lesions showed a picture of glioma with anaplastic astrocytes. The patient received a ventriculoperitoneal shunt operation and palliative chemotherapy, but died at 3 months of age. Autopsy was performed. Histological studies, which included immunohistochemical stains of the thalamic tumor, showed small, round, primitive, neoplastic cells with focal astrocytic differentiation.",

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AU - Ho, Donald M.

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AB - A cerebral primitive neuroectodermal tumor with astrocytic differentiation and extracranial metastases in a 28-day-old infant is reported. The infant presented with a progressively enlarged head, cutaneous lesions in the neck, and enlarged cervical lymph nodes. A computed tomography brain scan demonstrated a giant thalamic tumor with subarachnoid dissemination and hydrocephalus. Biopsy material from the cervical lesions showed a picture of glioma with anaplastic astrocytes. The patient received a ventriculoperitoneal shunt operation and palliative chemotherapy, but died at 3 months of age. Autopsy was performed. Histological studies, which included immunohistochemical stains of the thalamic tumor, showed small, round, primitive, neoplastic cells with focal astrocytic differentiation.

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