Abstract
A cerebral primitive neuroectodermal tumor with astrocytic differentiation and extracranial metastases in a 28-day-old infant is reported. The infant presented with a progressively enlarged head, cutaneous lesions in the neck, and enlarged cervical lymph nodes. A computed tomography brain scan demonstrated a giant thalamic tumor with subarachnoid dissemination and hydrocephalus. Biopsy material from the cervical lesions showed a picture of glioma with anaplastic astrocytes. The patient received a ventriculoperitoneal shunt operation and palliative chemotherapy, but died at 3 months of age. Autopsy was performed. Histological studies, which included immunohistochemical stains of the thalamic tumor, showed small, round, primitive, neoplastic cells with focal astrocytic differentiation.
Original language | English |
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Pages (from-to) | 179-182 |
Number of pages | 4 |
Journal | Child's Nervous System |
Volume | 6 |
Issue number | 3 |
DOIs | |
Publication status | Published - May 1 1990 |
Externally published | Yes |
Keywords
- Astròcytic differentiation
- Extracranial metastases
- Primitive neuroectodermal tumor
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Clinical Neurology