Congenital cerebral primitive neuroectodermal tumor with astrocytic differentiation and extracranial metastases

I. Ting Yu, Donald M. Ho, Tai-Tong Wong, Hung Chang Liu

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A cerebral primitive neuroectodermal tumor with astrocytic differentiation and extracranial metastases in a 28-day-old infant is reported. The infant presented with a progressively enlarged head, cutaneous lesions in the neck, and enlarged cervical lymph nodes. A computed tomography brain scan demonstrated a giant thalamic tumor with subarachnoid dissemination and hydrocephalus. Biopsy material from the cervical lesions showed a picture of glioma with anaplastic astrocytes. The patient received a ventriculoperitoneal shunt operation and palliative chemotherapy, but died at 3 months of age. Autopsy was performed. Histological studies, which included immunohistochemical stains of the thalamic tumor, showed small, round, primitive, neoplastic cells with focal astrocytic differentiation.

Original languageEnglish
Pages (from-to)179-182
Number of pages4
JournalChild's Nervous System
Volume6
Issue number3
DOIs
Publication statusPublished - May 1 1990
Externally publishedYes

Keywords

  • Astròcytic differentiation
  • Extracranial metastases
  • Primitive neuroectodermal tumor

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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