Abstract
A cerebral primitive neuroectodermal tumor with astrocytic differentiation and extracranial metastases in a 28-day-old infant is reported. The infant presented with a progressively enlarged head, cutaneous lesions in the neck, and enlarged cervical lymph nodes. A computed tomography brain scan demonstrated a giant thalamic tumor with subarachnoid dissemination and hydrocephalus. Biopsy material from the cervical lesions showed a picture of glioma with anaplastic astrocytes. The patient received a ventriculoperitoneal shunt operation and palliative chemotherapy, but died at 3 months of age. Autopsy was performed. Histological studies, which included immunohistochemical stains of the thalamic tumor, showed small, round, primitive, neoplastic cells with focal astrocytic differentiation.
| Original language | English |
|---|---|
| Pages (from-to) | 179-182 |
| Number of pages | 4 |
| Journal | Child's Nervous System |
| Volume | 6 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - May 1 1990 |
| Externally published | Yes |
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Keywords
- Astròcytic differentiation
- Extracranial metastases
- Primitive neuroectodermal tumor
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Clinical Neurology
Cite this
Congenital cerebral primitive neuroectodermal tumor with astrocytic differentiation and extracranial metastases. / Yu, I. Ting; Ho, Donald M.; Wong, Tai-Tong; Liu, Hung Chang.
In: Child's Nervous System, Vol. 6, No. 3, 01.05.1990, p. 179-182.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Congenital cerebral primitive neuroectodermal tumor with astrocytic differentiation and extracranial metastases
AU - Yu, I. Ting
AU - Ho, Donald M.
AU - Wong, Tai-Tong
AU - Liu, Hung Chang
PY - 1990/5/1
Y1 - 1990/5/1
N2 - A cerebral primitive neuroectodermal tumor with astrocytic differentiation and extracranial metastases in a 28-day-old infant is reported. The infant presented with a progressively enlarged head, cutaneous lesions in the neck, and enlarged cervical lymph nodes. A computed tomography brain scan demonstrated a giant thalamic tumor with subarachnoid dissemination and hydrocephalus. Biopsy material from the cervical lesions showed a picture of glioma with anaplastic astrocytes. The patient received a ventriculoperitoneal shunt operation and palliative chemotherapy, but died at 3 months of age. Autopsy was performed. Histological studies, which included immunohistochemical stains of the thalamic tumor, showed small, round, primitive, neoplastic cells with focal astrocytic differentiation.
AB - A cerebral primitive neuroectodermal tumor with astrocytic differentiation and extracranial metastases in a 28-day-old infant is reported. The infant presented with a progressively enlarged head, cutaneous lesions in the neck, and enlarged cervical lymph nodes. A computed tomography brain scan demonstrated a giant thalamic tumor with subarachnoid dissemination and hydrocephalus. Biopsy material from the cervical lesions showed a picture of glioma with anaplastic astrocytes. The patient received a ventriculoperitoneal shunt operation and palliative chemotherapy, but died at 3 months of age. Autopsy was performed. Histological studies, which included immunohistochemical stains of the thalamic tumor, showed small, round, primitive, neoplastic cells with focal astrocytic differentiation.
KW - Astròcytic differentiation
KW - Extracranial metastases
KW - Primitive neuroectodermal tumor
UR - http://www.scopus.com/inward/record.url?scp=0025367743&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025367743&partnerID=8YFLogxK
U2 - 10.1007/BF00308497
DO - 10.1007/BF00308497
M3 - Article
C2 - 2162735
AN - SCOPUS:0025367743
VL - 6
SP - 179
EP - 182
JO - Child's Nervous System
JF - Child's Nervous System
SN - 0256-7040
IS - 3
ER -