Concomitant Catheter-directed Transhepatic Thrombolysis and Selective Superior Mesenteric Artery Infusion in a Young Woman with Recent Portal Vein Thrombosis

Research output: Contribution to conferencePoster

Abstract

INTRODUCTION: Patients with portal vein thrombosis (PVT) may be asymptomatic but the consequences can be
severe. Early detection and treatment is crucial to avoid the severe consequences. Catheter-directed thrombolysis
(CDT) with anticoagulation played an important role in PVT in recent years. We present a case with concomitant
catheter-directed transhepatic thrombolysis and selective superior mesenteric artery infusion with urokinase and
heparin.
CASE REPORT: A 22-year-old woman had intermittent abdominal dull pain for 3 weeks. Computed tomography
revealed PVT. We performed concomitant catheter-directed transhepatic thrombolysis and selective superior
mesenteric artery infusion with urokinase and heparin. After 4-days thrombolysis treatment, the symptoms dissolved
and the follow-up ultrasound three months after discharge revealed patent portal vein without thrombosis.
DISCUSSION: Urokinase and heparin are widely used in thrombolysis of peripheral and central vascular thrombosis.
Thrombolysis for PVT can be performed via trans-arterial or transhepatic routes. Combination of these two methods
costs more time but offers ideal result. Awareness of the possible bleeding complication during infusion of the
thrombolytic agents is important.
Original languageEnglish
Publication statusPublished - Mar 2014
EventThe 63rd Annual Meeting of RSROC - Chung Shan Medical University, Taichung, Taiwan
Duration: Mar 22 2014Mar 23 2014
https://www.rsroc.org.tw/annual/annualnews_detail.asp?id=64

Conference

ConferenceThe 63rd Annual Meeting of RSROC
CountryTaiwan
CityTaichung
Period3/22/143/23/14
Internet address

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Superior Mesenteric Artery
Portal Vein
Thrombosis
Catheters
Urokinase-Type Plasminogen Activator
Heparin
Abdominal Pain
Blood Vessels
Arteries
Hemorrhage
Therapeutics

Cite this

Concomitant Catheter-directed Transhepatic Thrombolysis and Selective Superior Mesenteric Artery Infusion in a Young Woman with Recent Portal Vein Thrombosis. / Chang, Po-Yen; Chen, Chia-Yuen; Chan, Wing P.

2014. Poster session presented at The 63rd Annual Meeting of RSROC, Taichung, Taiwan.

Research output: Contribution to conferencePoster

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title = "Concomitant Catheter-directed Transhepatic Thrombolysis and Selective Superior Mesenteric Artery Infusion in a Young Woman with Recent Portal Vein Thrombosis",
abstract = "INTRODUCTION: Patients with portal vein thrombosis (PVT) may be asymptomatic but the consequences can besevere. Early detection and treatment is crucial to avoid the severe consequences. Catheter-directed thrombolysis(CDT) with anticoagulation played an important role in PVT in recent years. We present a case with concomitantcatheter-directed transhepatic thrombolysis and selective superior mesenteric artery infusion with urokinase andheparin.CASE REPORT: A 22-year-old woman had intermittent abdominal dull pain for 3 weeks. Computed tomographyrevealed PVT. We performed concomitant catheter-directed transhepatic thrombolysis and selective superiormesenteric artery infusion with urokinase and heparin. After 4-days thrombolysis treatment, the symptoms dissolvedand the follow-up ultrasound three months after discharge revealed patent portal vein without thrombosis.DISCUSSION: Urokinase and heparin are widely used in thrombolysis of peripheral and central vascular thrombosis.Thrombolysis for PVT can be performed via trans-arterial or transhepatic routes. Combination of these two methodscosts more time but offers ideal result. Awareness of the possible bleeding complication during infusion of thethrombolytic agents is important.",
author = "Po-Yen Chang and Chia-Yuen Chen and Chan, {Wing P.}",
year = "2014",
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language = "English",
note = "The 63rd Annual Meeting of RSROC ; Conference date: 22-03-2014 Through 23-03-2014",
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T1 - Concomitant Catheter-directed Transhepatic Thrombolysis and Selective Superior Mesenteric Artery Infusion in a Young Woman with Recent Portal Vein Thrombosis

AU - Chang, Po-Yen

AU - Chen, Chia-Yuen

AU - Chan, Wing P.

PY - 2014/3

Y1 - 2014/3

N2 - INTRODUCTION: Patients with portal vein thrombosis (PVT) may be asymptomatic but the consequences can besevere. Early detection and treatment is crucial to avoid the severe consequences. Catheter-directed thrombolysis(CDT) with anticoagulation played an important role in PVT in recent years. We present a case with concomitantcatheter-directed transhepatic thrombolysis and selective superior mesenteric artery infusion with urokinase andheparin.CASE REPORT: A 22-year-old woman had intermittent abdominal dull pain for 3 weeks. Computed tomographyrevealed PVT. We performed concomitant catheter-directed transhepatic thrombolysis and selective superiormesenteric artery infusion with urokinase and heparin. After 4-days thrombolysis treatment, the symptoms dissolvedand the follow-up ultrasound three months after discharge revealed patent portal vein without thrombosis.DISCUSSION: Urokinase and heparin are widely used in thrombolysis of peripheral and central vascular thrombosis.Thrombolysis for PVT can be performed via trans-arterial or transhepatic routes. Combination of these two methodscosts more time but offers ideal result. Awareness of the possible bleeding complication during infusion of thethrombolytic agents is important.

AB - INTRODUCTION: Patients with portal vein thrombosis (PVT) may be asymptomatic but the consequences can besevere. Early detection and treatment is crucial to avoid the severe consequences. Catheter-directed thrombolysis(CDT) with anticoagulation played an important role in PVT in recent years. We present a case with concomitantcatheter-directed transhepatic thrombolysis and selective superior mesenteric artery infusion with urokinase andheparin.CASE REPORT: A 22-year-old woman had intermittent abdominal dull pain for 3 weeks. Computed tomographyrevealed PVT. We performed concomitant catheter-directed transhepatic thrombolysis and selective superiormesenteric artery infusion with urokinase and heparin. After 4-days thrombolysis treatment, the symptoms dissolvedand the follow-up ultrasound three months after discharge revealed patent portal vein without thrombosis.DISCUSSION: Urokinase and heparin are widely used in thrombolysis of peripheral and central vascular thrombosis.Thrombolysis for PVT can be performed via trans-arterial or transhepatic routes. Combination of these two methodscosts more time but offers ideal result. Awareness of the possible bleeding complication during infusion of thethrombolytic agents is important.

M3 - Poster

ER -