Computer-aided strain evaluation for acoustic radiation force impulse imaging of breast masses

Chung Ming Lo, Yen Po Chen, Yeun Chung Chang, Chiao Lo, Chiun Sheng Huang, Ruey Feng Chang

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Acoustic radiation force impulse (ARFI) is a newly developed elastography technique that uses acoustic radiation force to provide additional stiffness information to conventional sonography. A computer-aided diagnosis (CAD) system was proposed to automatically specify the tumor boundaries in ARFI images and quantify the statistical stiffness information to reduce user dependence. The level-set segmentation was used to delineate tumor boundaries in B-mode images, and the segmented boundaries were then mapped to the corresponding area in ARFI images for a gray-scale calculation. A total of 61 benign and 51 malignant tumors were evaluated in the experiment. The CAD system based on the proposed ARFI features achieved an accuracy of 80% (90/112), a sensitivity of 80% (41/51), and a specificity of 80% (49/61), which is significantly better than that of the quantitative B-mode features (p <0.05). The ARFI features were further combined with the B-mode features, including shape and texture features, to further improve performance (area under the curve [AUC], 0.90 vs. 0.86). In conclusion, the CAD system based on the proposed ARFI features is a promising and efficient diagnostic method.

Original languageEnglish
Pages (from-to)151-166
Number of pages16
JournalUltrasonic Imaging
Volume36
Issue number3
DOIs
Publication statusPublished - 2014
Externally publishedYes

Keywords

  • Acoustic radiation force impulse
  • Breast cancer
  • Computer-aided diagnosis
  • Ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Fingerprint Dive into the research topics of 'Computer-aided strain evaluation for acoustic radiation force impulse imaging of breast masses'. Together they form a unique fingerprint.

Cite this