COMPLICATION OF BONE-MARROW TRANSPLANTATION GRAFT-VERSUS-HOST DISEASE RESULTING FROM CHRONIC-MYELOGENOUS-LEUKÆMIA LEUCOCYTE TRANSFUSIONS

Robert G. Graw, Jacqueline Whang-Peng, Gerhard Krüger, C. Dean Buckner, Brigid G. Leventhal, Costan Berard, Edward S. Henderson

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

Allogeneic bone-marrow transplantation was attempted in a 12-year-old boy with acute lymphocytic leukæmia. Chronicmyelogenous-leukæmia leucocytes transfused during a period of granulocytopenia became engrafted and resulted in graft-versus-host disease. Allogeneic blood-products should not be transfused into patients with severe drug or irradiation induced immunosuppression without prior in-vitro X-irradiation.

Original languageEnglish
Pages (from-to)338-341
Number of pages4
JournalThe Lancet
Volume296
Issue number7668
DOIs
Publication statusPublished - Aug 15 1970
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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