COMPLICATION OF BONE-MARROW TRANSPLANTATION GRAFT-VERSUS-HOST DISEASE RESULTING FROM CHRONIC-MYELOGENOUS-LEUKÆMIA LEUCOCYTE TRANSFUSIONS

Robert G. Graw, Jacqueline Whang-Peng, Gerhard Krüger, C. Dean Buckner, Brigid G. Leventhal, Costan Berard, Edward S. Henderson

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

Allogeneic bone-marrow transplantation was attempted in a 12-year-old boy with acute lymphocytic leukæmia. Chronicmyelogenous-leukæmia leucocytes transfused during a period of granulocytopenia became engrafted and resulted in graft-versus-host disease. Allogeneic blood-products should not be transfused into patients with severe drug or irradiation induced immunosuppression without prior in-vitro X-irradiation.

Original languageEnglish
Pages (from-to)338-341
Number of pages4
JournalThe Lancet
Volume296
Issue number7668
DOIs
Publication statusPublished - Aug 15 1970
Externally publishedYes

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Leukocyte Transfusion
Agranulocytosis
Homologous Transplantation
Graft vs Host Disease
Bone Marrow Transplantation
Immunosuppression
Leukocytes
Pharmaceutical Preparations
In Vitro Techniques

ASJC Scopus subject areas

  • Medicine(all)

Cite this

COMPLICATION OF BONE-MARROW TRANSPLANTATION GRAFT-VERSUS-HOST DISEASE RESULTING FROM CHRONIC-MYELOGENOUS-LEUKÆMIA LEUCOCYTE TRANSFUSIONS. / Graw, Robert G.; Whang-Peng, Jacqueline; Krüger, Gerhard; Buckner, C. Dean; Leventhal, Brigid G.; Berard, Costan; Henderson, Edward S.

In: The Lancet, Vol. 296, No. 7668, 15.08.1970, p. 338-341.

Research output: Contribution to journalArticle

Graw, Robert G. ; Whang-Peng, Jacqueline ; Krüger, Gerhard ; Buckner, C. Dean ; Leventhal, Brigid G. ; Berard, Costan ; Henderson, Edward S. / COMPLICATION OF BONE-MARROW TRANSPLANTATION GRAFT-VERSUS-HOST DISEASE RESULTING FROM CHRONIC-MYELOGENOUS-LEUKÆMIA LEUCOCYTE TRANSFUSIONS. In: The Lancet. 1970 ; Vol. 296, No. 7668. pp. 338-341.
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