Complicated intra-abdominal infections in a worldwide context: An observational prospective study (CIAOW Study)

Massimo Sartelli, Fausto Catena, Luca Ansaloni, Ernest Moore, Mark Malangoni, George Velmahos, Raul Coimbra, Kaoru Koike, Ari Leppaniemi, Walter Biffl, Zsolt Balogh, Cino Bendinelli, Sanjay Gupta, Yoram Kluger, Ferdinando Agresta, Salomone di Saverio, Gregorio Tugnoli, Elio Jovine, Carlos Ordonez, Carlos Augusto GomesGerson Alves Pereira Junior, Kuo Ching Yuan, Miklosh Bala, Miroslav P. Peev, Yunfeng Cui, Sanjay Marwah, Sanoop Zachariah, Boris Sakakushev, Victor Kong, Adamu Ahmed, Ashraf Abbas, Ricardo Alessandro Teixeira Gonsaga, Gianluca Guercioni, Nereo Vettoretto, Elia Poiasina, Offir Ben-Ishay, Rafael Díaz-Nieto, Damien Massalou, Matej Skrovina, Ihor Gerych, Goran Augustin, Jakub Kenig, Vladimir Khokha, Cristian Tranà, Kenneth Yuh Yen Kok, Alain Chichom Mefire, Jae Gil Lee, Suk Kyung Hong, Helmut Alfredo Segovia Lohse, Wagih Ghnnam, Alfredo Verni, Varut Lohsiriwat, Boonying Siribumrungwong, Alberto Tavares, Gianluca Baiocchi, Koray Das, Julien Jarry, Maurice Zida, Norio Sato, Kiyoshi Murata, Tomohisa Shoko, Takayuki Irahara, Ahmed O. Hamedelneel, Noel Naidoo, Abdul Rashid Kayode Adesunkanmi, Yoshiro Kobe, A. K. Attri, Rajeev Sharma, Federico Coccolini, Tamer El Zalabany, Khalid Al Khalifa, Juan Sanjuan, Rita Barnabé, Wataru Ishii

Research output: Contribution to journalReview article

27 Citations (Scopus)

Abstract

Despite advances in diagnosis, surgery, and antimicrobial therapy, mortality rates associated with complicated intra-abdominal infections remain exceedingly high. The World Society of Emergency Surgery (WSES) has designed the CIAOW study in order to describe the clinical, microbiological, and management-related profiles of both community- and healthcare-acquired complicated intra-abdominal infections in a worldwide context. The CIAOW study (Complicated Intra-Abdominal infection Observational Worldwide Study) is a multicenter observational study currently underway in 57 medical institutions worldwide. The study includes patients undergoing surgery or interventional drainage to address complicated intra-abdominal infections. This preliminary report includes all data from almost the first two months of the six-month study period. Patients who met inclusion criteria with either community-acquired or healthcare-associated complicated intra-abdominal infections (IAIs) were included in the study. 702 patients with a mean age of 49.2 years (range 18-98) were enrolled in the study. 272 patients (38.7%) were women and 430 (62.3%) were men. Among these patients, 615 (87.6%) were affected by community-acquired IAIs while the remaining 87 (12.4%) suffered from healthcare-associated infections. Generalized peritonitis was observed in 304 patients (43.3%), whereas localized peritonitis or abscesses was registered in 398 (57.7%) patients.The overall mortality rate was 10.1% (71/702). The final results of the CIAOW Study will be published following the conclusion of the study period in March 2013.

Original languageEnglish
Article number1
JournalWorld Journal of Emergency Surgery
Volume8
Issue number1
DOIs
Publication statusPublished - Jan 3 2013
Externally publishedYes

Fingerprint

Intraabdominal Infections
Observational Studies
Prospective Studies
Peritonitis
Community-Acquired Infections
Community Health Services
Mortality
Cross Infection
Abscess
Multicenter Studies
Drainage
Emergencies
Delivery of Health Care

ASJC Scopus subject areas

  • Surgery
  • Emergency Medicine

Cite this

Complicated intra-abdominal infections in a worldwide context : An observational prospective study (CIAOW Study). / Sartelli, Massimo; Catena, Fausto; Ansaloni, Luca; Moore, Ernest; Malangoni, Mark; Velmahos, George; Coimbra, Raul; Koike, Kaoru; Leppaniemi, Ari; Biffl, Walter; Balogh, Zsolt; Bendinelli, Cino; Gupta, Sanjay; Kluger, Yoram; Agresta, Ferdinando; di Saverio, Salomone; Tugnoli, Gregorio; Jovine, Elio; Ordonez, Carlos; Gomes, Carlos Augusto; Junior, Gerson Alves Pereira; Yuan, Kuo Ching; Bala, Miklosh; Peev, Miroslav P.; Cui, Yunfeng; Marwah, Sanjay; Zachariah, Sanoop; Sakakushev, Boris; Kong, Victor; Ahmed, Adamu; Abbas, Ashraf; Gonsaga, Ricardo Alessandro Teixeira; Guercioni, Gianluca; Vettoretto, Nereo; Poiasina, Elia; Ben-Ishay, Offir; Díaz-Nieto, Rafael; Massalou, Damien; Skrovina, Matej; Gerych, Ihor; Augustin, Goran; Kenig, Jakub; Khokha, Vladimir; Tranà, Cristian; Kok, Kenneth Yuh Yen; Mefire, Alain Chichom; Lee, Jae Gil; Hong, Suk Kyung; Lohse, Helmut Alfredo Segovia; Ghnnam, Wagih; Verni, Alfredo; Lohsiriwat, Varut; Siribumrungwong, Boonying; Tavares, Alberto; Baiocchi, Gianluca; Das, Koray; Jarry, Julien; Zida, Maurice; Sato, Norio; Murata, Kiyoshi; Shoko, Tomohisa; Irahara, Takayuki; Hamedelneel, Ahmed O.; Naidoo, Noel; Adesunkanmi, Abdul Rashid Kayode; Kobe, Yoshiro; Attri, A. K.; Sharma, Rajeev; Coccolini, Federico; El Zalabany, Tamer; Khalifa, Khalid Al; Sanjuan, Juan; Barnabé, Rita; Ishii, Wataru.

In: World Journal of Emergency Surgery, Vol. 8, No. 1, 1, 03.01.2013.

Research output: Contribution to journalReview article

Sartelli, M, Catena, F, Ansaloni, L, Moore, E, Malangoni, M, Velmahos, G, Coimbra, R, Koike, K, Leppaniemi, A, Biffl, W, Balogh, Z, Bendinelli, C, Gupta, S, Kluger, Y, Agresta, F, di Saverio, S, Tugnoli, G, Jovine, E, Ordonez, C, Gomes, CA, Junior, GAP, Yuan, KC, Bala, M, Peev, MP, Cui, Y, Marwah, S, Zachariah, S, Sakakushev, B, Kong, V, Ahmed, A, Abbas, A, Gonsaga, RAT, Guercioni, G, Vettoretto, N, Poiasina, E, Ben-Ishay, O, Díaz-Nieto, R, Massalou, D, Skrovina, M, Gerych, I, Augustin, G, Kenig, J, Khokha, V, Tranà, C, Kok, KYY, Mefire, AC, Lee, JG, Hong, SK, Lohse, HAS, Ghnnam, W, Verni, A, Lohsiriwat, V, Siribumrungwong, B, Tavares, A, Baiocchi, G, Das, K, Jarry, J, Zida, M, Sato, N, Murata, K, Shoko, T, Irahara, T, Hamedelneel, AO, Naidoo, N, Adesunkanmi, ARK, Kobe, Y, Attri, AK, Sharma, R, Coccolini, F, El Zalabany, T, Khalifa, KA, Sanjuan, J, Barnabé, R & Ishii, W 2013, 'Complicated intra-abdominal infections in a worldwide context: An observational prospective study (CIAOW Study)', World Journal of Emergency Surgery, vol. 8, no. 1, 1. https://doi.org/10.1186/1749-7922-8-1
Sartelli, Massimo ; Catena, Fausto ; Ansaloni, Luca ; Moore, Ernest ; Malangoni, Mark ; Velmahos, George ; Coimbra, Raul ; Koike, Kaoru ; Leppaniemi, Ari ; Biffl, Walter ; Balogh, Zsolt ; Bendinelli, Cino ; Gupta, Sanjay ; Kluger, Yoram ; Agresta, Ferdinando ; di Saverio, Salomone ; Tugnoli, Gregorio ; Jovine, Elio ; Ordonez, Carlos ; Gomes, Carlos Augusto ; Junior, Gerson Alves Pereira ; Yuan, Kuo Ching ; Bala, Miklosh ; Peev, Miroslav P. ; Cui, Yunfeng ; Marwah, Sanjay ; Zachariah, Sanoop ; Sakakushev, Boris ; Kong, Victor ; Ahmed, Adamu ; Abbas, Ashraf ; Gonsaga, Ricardo Alessandro Teixeira ; Guercioni, Gianluca ; Vettoretto, Nereo ; Poiasina, Elia ; Ben-Ishay, Offir ; Díaz-Nieto, Rafael ; Massalou, Damien ; Skrovina, Matej ; Gerych, Ihor ; Augustin, Goran ; Kenig, Jakub ; Khokha, Vladimir ; Tranà, Cristian ; Kok, Kenneth Yuh Yen ; Mefire, Alain Chichom ; Lee, Jae Gil ; Hong, Suk Kyung ; Lohse, Helmut Alfredo Segovia ; Ghnnam, Wagih ; Verni, Alfredo ; Lohsiriwat, Varut ; Siribumrungwong, Boonying ; Tavares, Alberto ; Baiocchi, Gianluca ; Das, Koray ; Jarry, Julien ; Zida, Maurice ; Sato, Norio ; Murata, Kiyoshi ; Shoko, Tomohisa ; Irahara, Takayuki ; Hamedelneel, Ahmed O. ; Naidoo, Noel ; Adesunkanmi, Abdul Rashid Kayode ; Kobe, Yoshiro ; Attri, A. K. ; Sharma, Rajeev ; Coccolini, Federico ; El Zalabany, Tamer ; Khalifa, Khalid Al ; Sanjuan, Juan ; Barnabé, Rita ; Ishii, Wataru. / Complicated intra-abdominal infections in a worldwide context : An observational prospective study (CIAOW Study). In: World Journal of Emergency Surgery. 2013 ; Vol. 8, No. 1.
@article{85aebde8f737426496b7b3d57449ad13,
title = "Complicated intra-abdominal infections in a worldwide context: An observational prospective study (CIAOW Study)",
abstract = "Despite advances in diagnosis, surgery, and antimicrobial therapy, mortality rates associated with complicated intra-abdominal infections remain exceedingly high. The World Society of Emergency Surgery (WSES) has designed the CIAOW study in order to describe the clinical, microbiological, and management-related profiles of both community- and healthcare-acquired complicated intra-abdominal infections in a worldwide context. The CIAOW study (Complicated Intra-Abdominal infection Observational Worldwide Study) is a multicenter observational study currently underway in 57 medical institutions worldwide. The study includes patients undergoing surgery or interventional drainage to address complicated intra-abdominal infections. This preliminary report includes all data from almost the first two months of the six-month study period. Patients who met inclusion criteria with either community-acquired or healthcare-associated complicated intra-abdominal infections (IAIs) were included in the study. 702 patients with a mean age of 49.2 years (range 18-98) were enrolled in the study. 272 patients (38.7{\%}) were women and 430 (62.3{\%}) were men. Among these patients, 615 (87.6{\%}) were affected by community-acquired IAIs while the remaining 87 (12.4{\%}) suffered from healthcare-associated infections. Generalized peritonitis was observed in 304 patients (43.3{\%}), whereas localized peritonitis or abscesses was registered in 398 (57.7{\%}) patients.The overall mortality rate was 10.1{\%} (71/702). The final results of the CIAOW Study will be published following the conclusion of the study period in March 2013.",
author = "Massimo Sartelli and Fausto Catena and Luca Ansaloni and Ernest Moore and Mark Malangoni and George Velmahos and Raul Coimbra and Kaoru Koike and Ari Leppaniemi and Walter Biffl and Zsolt Balogh and Cino Bendinelli and Sanjay Gupta and Yoram Kluger and Ferdinando Agresta and {di Saverio}, Salomone and Gregorio Tugnoli and Elio Jovine and Carlos Ordonez and Gomes, {Carlos Augusto} and Junior, {Gerson Alves Pereira} and Yuan, {Kuo Ching} and Miklosh Bala and Peev, {Miroslav P.} and Yunfeng Cui and Sanjay Marwah and Sanoop Zachariah and Boris Sakakushev and Victor Kong and Adamu Ahmed and Ashraf Abbas and Gonsaga, {Ricardo Alessandro Teixeira} and Gianluca Guercioni and Nereo Vettoretto and Elia Poiasina and Offir Ben-Ishay and Rafael D{\'i}az-Nieto and Damien Massalou and Matej Skrovina and Ihor Gerych and Goran Augustin and Jakub Kenig and Vladimir Khokha and Cristian Tran{\`a} and Kok, {Kenneth Yuh Yen} and Mefire, {Alain Chichom} and Lee, {Jae Gil} and Hong, {Suk Kyung} and Lohse, {Helmut Alfredo Segovia} and Wagih Ghnnam and Alfredo Verni and Varut Lohsiriwat and Boonying Siribumrungwong and Alberto Tavares and Gianluca Baiocchi and Koray Das and Julien Jarry and Maurice Zida and Norio Sato and Kiyoshi Murata and Tomohisa Shoko and Takayuki Irahara and Hamedelneel, {Ahmed O.} and Noel Naidoo and Adesunkanmi, {Abdul Rashid Kayode} and Yoshiro Kobe and Attri, {A. K.} and Rajeev Sharma and Federico Coccolini and {El Zalabany}, Tamer and Khalifa, {Khalid Al} and Juan Sanjuan and Rita Barnab{\'e} and Wataru Ishii",
year = "2013",
month = "1",
day = "3",
doi = "10.1186/1749-7922-8-1",
language = "English",
volume = "8",
journal = "World Journal of Emergency Surgery",
issn = "1749-7922",
publisher = "BioMed Central",
number = "1",

}

TY - JOUR

T1 - Complicated intra-abdominal infections in a worldwide context

T2 - An observational prospective study (CIAOW Study)

AU - Sartelli, Massimo

AU - Catena, Fausto

AU - Ansaloni, Luca

AU - Moore, Ernest

AU - Malangoni, Mark

AU - Velmahos, George

AU - Coimbra, Raul

AU - Koike, Kaoru

AU - Leppaniemi, Ari

AU - Biffl, Walter

AU - Balogh, Zsolt

AU - Bendinelli, Cino

AU - Gupta, Sanjay

AU - Kluger, Yoram

AU - Agresta, Ferdinando

AU - di Saverio, Salomone

AU - Tugnoli, Gregorio

AU - Jovine, Elio

AU - Ordonez, Carlos

AU - Gomes, Carlos Augusto

AU - Junior, Gerson Alves Pereira

AU - Yuan, Kuo Ching

AU - Bala, Miklosh

AU - Peev, Miroslav P.

AU - Cui, Yunfeng

AU - Marwah, Sanjay

AU - Zachariah, Sanoop

AU - Sakakushev, Boris

AU - Kong, Victor

AU - Ahmed, Adamu

AU - Abbas, Ashraf

AU - Gonsaga, Ricardo Alessandro Teixeira

AU - Guercioni, Gianluca

AU - Vettoretto, Nereo

AU - Poiasina, Elia

AU - Ben-Ishay, Offir

AU - Díaz-Nieto, Rafael

AU - Massalou, Damien

AU - Skrovina, Matej

AU - Gerych, Ihor

AU - Augustin, Goran

AU - Kenig, Jakub

AU - Khokha, Vladimir

AU - Tranà, Cristian

AU - Kok, Kenneth Yuh Yen

AU - Mefire, Alain Chichom

AU - Lee, Jae Gil

AU - Hong, Suk Kyung

AU - Lohse, Helmut Alfredo Segovia

AU - Ghnnam, Wagih

AU - Verni, Alfredo

AU - Lohsiriwat, Varut

AU - Siribumrungwong, Boonying

AU - Tavares, Alberto

AU - Baiocchi, Gianluca

AU - Das, Koray

AU - Jarry, Julien

AU - Zida, Maurice

AU - Sato, Norio

AU - Murata, Kiyoshi

AU - Shoko, Tomohisa

AU - Irahara, Takayuki

AU - Hamedelneel, Ahmed O.

AU - Naidoo, Noel

AU - Adesunkanmi, Abdul Rashid Kayode

AU - Kobe, Yoshiro

AU - Attri, A. K.

AU - Sharma, Rajeev

AU - Coccolini, Federico

AU - El Zalabany, Tamer

AU - Khalifa, Khalid Al

AU - Sanjuan, Juan

AU - Barnabé, Rita

AU - Ishii, Wataru

PY - 2013/1/3

Y1 - 2013/1/3

N2 - Despite advances in diagnosis, surgery, and antimicrobial therapy, mortality rates associated with complicated intra-abdominal infections remain exceedingly high. The World Society of Emergency Surgery (WSES) has designed the CIAOW study in order to describe the clinical, microbiological, and management-related profiles of both community- and healthcare-acquired complicated intra-abdominal infections in a worldwide context. The CIAOW study (Complicated Intra-Abdominal infection Observational Worldwide Study) is a multicenter observational study currently underway in 57 medical institutions worldwide. The study includes patients undergoing surgery or interventional drainage to address complicated intra-abdominal infections. This preliminary report includes all data from almost the first two months of the six-month study period. Patients who met inclusion criteria with either community-acquired or healthcare-associated complicated intra-abdominal infections (IAIs) were included in the study. 702 patients with a mean age of 49.2 years (range 18-98) were enrolled in the study. 272 patients (38.7%) were women and 430 (62.3%) were men. Among these patients, 615 (87.6%) were affected by community-acquired IAIs while the remaining 87 (12.4%) suffered from healthcare-associated infections. Generalized peritonitis was observed in 304 patients (43.3%), whereas localized peritonitis or abscesses was registered in 398 (57.7%) patients.The overall mortality rate was 10.1% (71/702). The final results of the CIAOW Study will be published following the conclusion of the study period in March 2013.

AB - Despite advances in diagnosis, surgery, and antimicrobial therapy, mortality rates associated with complicated intra-abdominal infections remain exceedingly high. The World Society of Emergency Surgery (WSES) has designed the CIAOW study in order to describe the clinical, microbiological, and management-related profiles of both community- and healthcare-acquired complicated intra-abdominal infections in a worldwide context. The CIAOW study (Complicated Intra-Abdominal infection Observational Worldwide Study) is a multicenter observational study currently underway in 57 medical institutions worldwide. The study includes patients undergoing surgery or interventional drainage to address complicated intra-abdominal infections. This preliminary report includes all data from almost the first two months of the six-month study period. Patients who met inclusion criteria with either community-acquired or healthcare-associated complicated intra-abdominal infections (IAIs) were included in the study. 702 patients with a mean age of 49.2 years (range 18-98) were enrolled in the study. 272 patients (38.7%) were women and 430 (62.3%) were men. Among these patients, 615 (87.6%) were affected by community-acquired IAIs while the remaining 87 (12.4%) suffered from healthcare-associated infections. Generalized peritonitis was observed in 304 patients (43.3%), whereas localized peritonitis or abscesses was registered in 398 (57.7%) patients.The overall mortality rate was 10.1% (71/702). The final results of the CIAOW Study will be published following the conclusion of the study period in March 2013.

UR - http://www.scopus.com/inward/record.url?scp=84871716714&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84871716714&partnerID=8YFLogxK

U2 - 10.1186/1749-7922-8-1

DO - 10.1186/1749-7922-8-1

M3 - Review article

AN - SCOPUS:84871716714

VL - 8

JO - World Journal of Emergency Surgery

JF - World Journal of Emergency Surgery

SN - 1749-7922

IS - 1

M1 - 1

ER -