Confronto della qualità della vita nei pazienti con carcinoma rinofaringeo dopo trattamento con differenti metodiche di RT

Translated title of the contribution: Comparisons of quality of life for patients with nasopharyngeal carcinoma after treatment with different RT technologies

L. Jang-Chun, H. Jing-Min, J. Yee-Min, L. Dai-Wei, C. Chang-Ming, L. Chun-Shu, H. Wen-Yen, S. Yu-Fu, L. Kuen-Tze, F. Chao-Yueh, L. Cheng-Hsiang, C. Hsing-Lung

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The objectives of this study were determine the quality of life (QoL) for patients with nasopharyngeal carcinoma (NPC) after treatment with different advanced technologies in radiotherapy (RT). A total of 150 patients with NPC were consecutively treated using curative RT in the Department of Radiation Oncology at Tri-service General Hospital in Taiwan. Data were collected prospectively from medical records and questionnaires. We used the Short-Form-36 (SF36) health survey questionnaire to evaluate general QoL, and a modified EORTC QLQ-H&N35 questionnaire to evaluate the correlation of xerostomia with QoL. The selection of RT methodology among two-dimensional radiotherapy (2D-RT), three-dimensional conformal radiotherapy (3D-CRT) and intensity-modulated radiotherapy (IMRT) was a significant factor for predicting difficulty of speech (P = 0.003), difficulty in chewing (P = 0.012), swallowing ability (P = 0.004), dry throat sensationas during meals (P = 0.006) and the frequency of drinking water to maintain a moist mouth (P = 0.01). Our data suggest that the intensitymodulated radiotherapy technique plays a significant role in improving the QoL of NPC patients in our study.

Translated title of the contributionComparisons of quality of life for patients with nasopharyngeal carcinoma after treatment with different RT technologies
Original languageItalian
Pages (from-to)241-246
Number of pages6
JournalActa Otorhinolaryngologica Italica
Volume34
Issue number4
Publication statusPublished - Jan 1 2014

Keywords

  • Intensity-modulated radiotherapy
  • Nasopharyngeal carcinoma

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Medicine(all)

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    Jang-Chun, L., Jing-Min, H., Yee-Min, J., Dai-Wei, L., Chang-Ming, C., Chun-Shu, L., Wen-Yen, H., Yu-Fu, S., Kuen-Tze, L., Chao-Yueh, F., Cheng-Hsiang, L., & Hsing-Lung, C. (2014). Confronto della qualità della vita nei pazienti con carcinoma rinofaringeo dopo trattamento con differenti metodiche di RT. Acta Otorhinolaryngologica Italica, 34(4), 241-246.