Background: The evaluation of palliative care quality can understand care quality and it can be as an evidence for improving quality. In order to understand the internal consistency of medical professionals, patients and caregiver, health care system needs to be assessed appropriation of patient and caregiver. Previously, some studies focused on the medical quality care for patients’ and caregivers' views without medical professionals assessing the same situation, therefore, leading to biases in health care system. Objectives: The purpose of this study was to compare the palliative care quality among patients, caregivers, and medical professionals. Method: The cross-sectional research design was conducted. We used the palliative care outcome scale to assess the palliative care quality among the patients, the caregivers, and the medical professionals at the same time. The data were collected from a palliative care unit of the teaching hospital in Taiwan. Result: The results showed that the palliative care quality of patients and caregivers was in accordance with medical professionals and in ideal situation. The scores of the items,“life worthwhile and information”, had statistical significant between patients and medical professionals. The medical professionals perceived the items, “life worthwhile and information”, were poor than those of the patients. The scores of the items, “life worthwhile, family anxiety, and personal affairs”, had statistical significant between caregivers and medical professionals (p＜0.05). The caregivers’ perceived the items,“family anxiety and personal affairs” were poor than those of medical professionals. The medical professionals’ perceived the item, “life worthwhile”, was poor than that of caregivers.Conclusion: Except the items, “information, life worthwhile, personal affairs, and family anxiety”, the scores of patients and caregivers were closed to those of the medical professionals. The results can be references to monitor continually the palliative care quality in the future.