Comparison of the effects of micro-osteoperforation and corticision on the rate of orthodontic tooth movement in rats

Chi-Yang Tasi, Teng Kai Yang, Hsueh-Yin Hsieh, Liang Yu Lin

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

OBJECTIVE: To investigate the effects of flapless micro-osteoperforation and corticision on the rate of orthodontic tooth movement in rats.

MATERIALS AND METHODS: Forty-five 8-week-old male Sprague-Dawley rats were divided into the following groups: micro-osteoperforation and orthodontic force (MOP + F), corticision and orthodontic force (C + F), and orthodontic force only (F, control). The left maxillary first molars were pulled forward with a force of 50 g. Flapless surgical interventions were conducted in the MOP + F and C + F groups. The total duration of the experiment was 6 weeks. Alveolar bone density and the number of osteoclasts were evaluated using microcomputed tomography and histologic examination, respectively.

RESULTS: The tooth movement distance was significantly higher in both experimental groups than in the control group. Bone density and bone mineral density decreased in the MOP + F and C + F groups. The number of osteoclasts in the MOP + F and C + F groups was significantly higher than in the control group F.

CONCLUSION: The two minimally invasive flapless surgical interventions increased bone remodeling and osteoclast activity and induced faster orthodontic tooth movement for at least 2 weeks in rats. No differences were observed between the outcome of flapless micro-osteoperforation and corticision in the rats.

Original languageEnglish
Pages (from-to)558-64
Number of pages7
JournalAngle Orthodontist
Volume86
Issue number4
DOIs
Publication statusPublished - Jul 2016

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Tooth Movement Techniques
Osteoclasts
Orthodontics
Bone Density
X-Ray Microtomography
Control Groups
Bone Remodeling
Sprague Dawley Rats
Bone and Bones

Keywords

  • Journal Article

Cite this

Comparison of the effects of micro-osteoperforation and corticision on the rate of orthodontic tooth movement in rats. / Tasi, Chi-Yang; Yang, Teng Kai; Hsieh, Hsueh-Yin; Lin, Liang Yu.

In: Angle Orthodontist, Vol. 86, No. 4, 07.2016, p. 558-64.

Research output: Contribution to journalArticle

Tasi, Chi-Yang ; Yang, Teng Kai ; Hsieh, Hsueh-Yin ; Lin, Liang Yu. / Comparison of the effects of micro-osteoperforation and corticision on the rate of orthodontic tooth movement in rats. In: Angle Orthodontist. 2016 ; Vol. 86, No. 4. pp. 558-64.
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N2 - OBJECTIVE: To investigate the effects of flapless micro-osteoperforation and corticision on the rate of orthodontic tooth movement in rats.MATERIALS AND METHODS: Forty-five 8-week-old male Sprague-Dawley rats were divided into the following groups: micro-osteoperforation and orthodontic force (MOP + F), corticision and orthodontic force (C + F), and orthodontic force only (F, control). The left maxillary first molars were pulled forward with a force of 50 g. Flapless surgical interventions were conducted in the MOP + F and C + F groups. The total duration of the experiment was 6 weeks. Alveolar bone density and the number of osteoclasts were evaluated using microcomputed tomography and histologic examination, respectively.RESULTS: The tooth movement distance was significantly higher in both experimental groups than in the control group. Bone density and bone mineral density decreased in the MOP + F and C + F groups. The number of osteoclasts in the MOP + F and C + F groups was significantly higher than in the control group F.CONCLUSION: The two minimally invasive flapless surgical interventions increased bone remodeling and osteoclast activity and induced faster orthodontic tooth movement for at least 2 weeks in rats. No differences were observed between the outcome of flapless micro-osteoperforation and corticision in the rats.

AB - OBJECTIVE: To investigate the effects of flapless micro-osteoperforation and corticision on the rate of orthodontic tooth movement in rats.MATERIALS AND METHODS: Forty-five 8-week-old male Sprague-Dawley rats were divided into the following groups: micro-osteoperforation and orthodontic force (MOP + F), corticision and orthodontic force (C + F), and orthodontic force only (F, control). The left maxillary first molars were pulled forward with a force of 50 g. Flapless surgical interventions were conducted in the MOP + F and C + F groups. The total duration of the experiment was 6 weeks. Alveolar bone density and the number of osteoclasts were evaluated using microcomputed tomography and histologic examination, respectively.RESULTS: The tooth movement distance was significantly higher in both experimental groups than in the control group. Bone density and bone mineral density decreased in the MOP + F and C + F groups. The number of osteoclasts in the MOP + F and C + F groups was significantly higher than in the control group F.CONCLUSION: The two minimally invasive flapless surgical interventions increased bone remodeling and osteoclast activity and induced faster orthodontic tooth movement for at least 2 weeks in rats. No differences were observed between the outcome of flapless micro-osteoperforation and corticision in the rats.

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