Comparison of lesion characteristics between conventional and high-power short-duration ablation using contact force-sensing catheter in patients with paroxysmal atrial fibrillation

Chun Chao Chen, Po Tseng Lee, Vu Van Ba, Chieh Mao Chuang, Yenn Jiang Lin, Li Wei Lo, Yu Feng Hu, Fa Po Chung, Chin Yu Lin, Ting Yung Chang, Jennifer Jeanne Vicera, Ting Chun Huang, Chih Min Liu, Cheng I. Wu, Isaiah C. Lugtu, Ankit Jain, Shih Lin Chang, Shih Ann Chen

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Transmural lesion creation is essential for effective atrial fibrillation (AF) ablation. Lesion characteristics between conventional energy and high-power short-duration (HPSD) setting in contact force-guided (CF) ablation for AF remained unclear. Methods: Eighty consecutive AF patients who received CF with conventional energy setting (power control: 25–30 W, force–time integral = 400 g s, n = 40) or with HPSD (power control: 40–50 W, 10 s, n = 40) ablation were analyzed. Of them, 15 patients in each conventional and HPSD group were matched by age and gender respectively for ablation lesions analysis. Type A and B lesions were defined as a lesion with and without significant voltage reduction after ablation, respectively. The anatomical distribution of these lesions and ablation outcomes among the 2 groups were analyzed. Results: 1615 and 1724 ablation lesions were analyzed in the conventional and HPSD groups, respectively. HPSD group had a higher proportion of type A lesion compared to conventional group (P < 0.01). In the conventional group, most type A lesions were at the right pulmonary vein (RPV) posterior wall (50.2%) whereas in the HPSD group, most type A lesions were at the RPV anterior wall (44.0%) (P = 0.04). The procedure time and ablation time were significantly shorter in the HPSD group than that in the conventional group (91.0 ± 12.1 vs. 124 ± 14.2 min, P = 0.03; 30.7 ± 19.2 vs. 57.8 ± 21 min, P = 0.02, respectively). At a mean follow-up period of 11 ± 1.4 months, there were 13 and 7 patients with recurrence in conventional and HPSD group respectively (P = 0.03). Conclusion: Optimal ablation lesion characteristics and distribution after conventional and HPSD ablation differed significantly. HPSD ablation had shorter ablation time and lower recurrence rate than did conventional ablation.

Original languageEnglish
Article number387
JournalBMC Cardiovascular Disorders
Volume21
Issue number1
DOIs
Publication statusPublished - Dec 2021

Keywords

  • Atrial fibrillation
  • Contact force-guided ablation
  • Force time integral
  • High-power short-duration ablation
  • Pulmonary vein isolation
  • Voltage

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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