Comparison of Laparoscopic Myomectomy Using in Situ Morcellation With and Without Uterine Artery Ligation for Treatment of Symptomatic Myomas

Wen Chun Chang, Pei Shen Huang, Peng Hui Wang, Daw Yuan Chang, Su Cheng Huang, Szu Yu Chen, Li Yun Chou, Bor Ching Sheu

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Study Objective: To evaluate the efficacy of laparoscopic uterine artery ligation (LUAL) before in situ morcellation (ISM) compared with ISM alone. Design: Prospective study (Canadian Task Force classification II-1). Setting: University-affiliated hospital. Patients: One hundred forty-four women with symptomatic uterine myomas, of whom 45 underwent LUAL and ISM and 99 underwent ISM only, from August 2007 through August 2009. Interventions: Ligation or no ligation of the uterine arteries before ISM. Measurements and Main Results: In the LUAL+ISM group compared with the ISM group, mean (SD) operative time was significantly longer (107 [34] minutes vs 93 [35] minutes; p = .03), and there was less intraoperative blood loss (84 [53] mL vs 137 [166] mL; p < .001). Eight patients in the ISM group (8.1%) required a blood transfusion, including 4 (4.0%) with excessive intraoperative bleeding and 4 (4.0%) with postoperative hematomas. Although myomas in the LUAL+ISM group weighed more (p < .001), none of the patients in that group had excessive intraoperative bleeding, postoperative hematomas, or required blood transfusion (p = .046). At 2 years of follow-up, in the LUAL+ISM group compared with the ISM group, the myoma recurrence rate was 7% vs 24%, and symptom improvement was reported by 98% of patients vs 86% (statistically significant). Conclusion: Laparoscopic myomectomy using an ISM technique with or without simultaneous LUAL may be used in the management of symptomatic uterine myomas; however, LUAL+ISM may result in a better surgical outcome.

Original languageEnglish
Pages (from-to)715-721
Number of pages7
JournalJournal of Minimally Invasive Gynecology
Volume19
Issue number6
DOIs
Publication statusPublished - Nov 1 2012
Externally publishedYes

Fingerprint

Uterine Myomectomy
Uterine Artery
Myoma
Ligation
Therapeutics
Blood Transfusion
Hematoma
Morcellation
Hemorrhage

Keywords

  • In situ morcellation
  • Laparoscopic uterine artery ligation
  • Myomectomy
  • Symptomatic myomas

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

Comparison of Laparoscopic Myomectomy Using in Situ Morcellation With and Without Uterine Artery Ligation for Treatment of Symptomatic Myomas. / Chang, Wen Chun; Huang, Pei Shen; Wang, Peng Hui; Chang, Daw Yuan; Huang, Su Cheng; Chen, Szu Yu; Chou, Li Yun; Sheu, Bor Ching.

In: Journal of Minimally Invasive Gynecology, Vol. 19, No. 6, 01.11.2012, p. 715-721.

Research output: Contribution to journalArticle

Chang, Wen Chun ; Huang, Pei Shen ; Wang, Peng Hui ; Chang, Daw Yuan ; Huang, Su Cheng ; Chen, Szu Yu ; Chou, Li Yun ; Sheu, Bor Ching. / Comparison of Laparoscopic Myomectomy Using in Situ Morcellation With and Without Uterine Artery Ligation for Treatment of Symptomatic Myomas. In: Journal of Minimally Invasive Gynecology. 2012 ; Vol. 19, No. 6. pp. 715-721.
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abstract = "Study Objective: To evaluate the efficacy of laparoscopic uterine artery ligation (LUAL) before in situ morcellation (ISM) compared with ISM alone. Design: Prospective study (Canadian Task Force classification II-1). Setting: University-affiliated hospital. Patients: One hundred forty-four women with symptomatic uterine myomas, of whom 45 underwent LUAL and ISM and 99 underwent ISM only, from August 2007 through August 2009. Interventions: Ligation or no ligation of the uterine arteries before ISM. Measurements and Main Results: In the LUAL+ISM group compared with the ISM group, mean (SD) operative time was significantly longer (107 [34] minutes vs 93 [35] minutes; p = .03), and there was less intraoperative blood loss (84 [53] mL vs 137 [166] mL; p < .001). Eight patients in the ISM group (8.1{\%}) required a blood transfusion, including 4 (4.0{\%}) with excessive intraoperative bleeding and 4 (4.0{\%}) with postoperative hematomas. Although myomas in the LUAL+ISM group weighed more (p < .001), none of the patients in that group had excessive intraoperative bleeding, postoperative hematomas, or required blood transfusion (p = .046). At 2 years of follow-up, in the LUAL+ISM group compared with the ISM group, the myoma recurrence rate was 7{\%} vs 24{\%}, and symptom improvement was reported by 98{\%} of patients vs 86{\%} (statistically significant). Conclusion: Laparoscopic myomectomy using an ISM technique with or without simultaneous LUAL may be used in the management of symptomatic uterine myomas; however, LUAL+ISM may result in a better surgical outcome.",
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T1 - Comparison of Laparoscopic Myomectomy Using in Situ Morcellation With and Without Uterine Artery Ligation for Treatment of Symptomatic Myomas

AU - Chang, Wen Chun

AU - Huang, Pei Shen

AU - Wang, Peng Hui

AU - Chang, Daw Yuan

AU - Huang, Su Cheng

AU - Chen, Szu Yu

AU - Chou, Li Yun

AU - Sheu, Bor Ching

PY - 2012/11/1

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N2 - Study Objective: To evaluate the efficacy of laparoscopic uterine artery ligation (LUAL) before in situ morcellation (ISM) compared with ISM alone. Design: Prospective study (Canadian Task Force classification II-1). Setting: University-affiliated hospital. Patients: One hundred forty-four women with symptomatic uterine myomas, of whom 45 underwent LUAL and ISM and 99 underwent ISM only, from August 2007 through August 2009. Interventions: Ligation or no ligation of the uterine arteries before ISM. Measurements and Main Results: In the LUAL+ISM group compared with the ISM group, mean (SD) operative time was significantly longer (107 [34] minutes vs 93 [35] minutes; p = .03), and there was less intraoperative blood loss (84 [53] mL vs 137 [166] mL; p < .001). Eight patients in the ISM group (8.1%) required a blood transfusion, including 4 (4.0%) with excessive intraoperative bleeding and 4 (4.0%) with postoperative hematomas. Although myomas in the LUAL+ISM group weighed more (p < .001), none of the patients in that group had excessive intraoperative bleeding, postoperative hematomas, or required blood transfusion (p = .046). At 2 years of follow-up, in the LUAL+ISM group compared with the ISM group, the myoma recurrence rate was 7% vs 24%, and symptom improvement was reported by 98% of patients vs 86% (statistically significant). Conclusion: Laparoscopic myomectomy using an ISM technique with or without simultaneous LUAL may be used in the management of symptomatic uterine myomas; however, LUAL+ISM may result in a better surgical outcome.

AB - Study Objective: To evaluate the efficacy of laparoscopic uterine artery ligation (LUAL) before in situ morcellation (ISM) compared with ISM alone. Design: Prospective study (Canadian Task Force classification II-1). Setting: University-affiliated hospital. Patients: One hundred forty-four women with symptomatic uterine myomas, of whom 45 underwent LUAL and ISM and 99 underwent ISM only, from August 2007 through August 2009. Interventions: Ligation or no ligation of the uterine arteries before ISM. Measurements and Main Results: In the LUAL+ISM group compared with the ISM group, mean (SD) operative time was significantly longer (107 [34] minutes vs 93 [35] minutes; p = .03), and there was less intraoperative blood loss (84 [53] mL vs 137 [166] mL; p < .001). Eight patients in the ISM group (8.1%) required a blood transfusion, including 4 (4.0%) with excessive intraoperative bleeding and 4 (4.0%) with postoperative hematomas. Although myomas in the LUAL+ISM group weighed more (p < .001), none of the patients in that group had excessive intraoperative bleeding, postoperative hematomas, or required blood transfusion (p = .046). At 2 years of follow-up, in the LUAL+ISM group compared with the ISM group, the myoma recurrence rate was 7% vs 24%, and symptom improvement was reported by 98% of patients vs 86% (statistically significant). Conclusion: Laparoscopic myomectomy using an ISM technique with or without simultaneous LUAL may be used in the management of symptomatic uterine myomas; however, LUAL+ISM may result in a better surgical outcome.

KW - In situ morcellation

KW - Laparoscopic uterine artery ligation

KW - Myomectomy

KW - Symptomatic myomas

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