Abstract
Background: The reliability of critical closing pressure (CrCP) estimates derived from peripheral blood pressure (BP) measurements is unclear. We attempted to evaluate the influences of peripheral circulation on determining CrCP. Methods: Twenty-five young healthy volunteers were studied. BP waves were obtained with plethysmography (Portapres) and carotid applanatory tonometry, respectively, for analysis. Transcranial Doppler was used to monitor cerebral flowvelocity. Using linear regression analysis, beat-to-beat CrCP was calculated at rest, during voluntary hyperventilation and during 5% CO2 inhalation. Results: Twenty of 25 participants demonstrating satisfactory tonometric tracings for both tests were included in the analysis. The systolic BP measured using plethysmography was higher than that derived from tonometry (139.4 ± 24.7 vs. 105.5 ± 29.6, p < 0.001). CrCP values derived from tonometry were all positive and higher than CrCP values derived from plethysmography (62.9 ± 19.9 vs. 11.1 ± 17.8, p < 0.001). The changes in CrCP induced by 5% CO2 inhalation and hyperventilation had a correlation between two BP monitoring methods (r = 0.52, p = 0.001). Conclusions: Pressure waveform is an important determinant in calculating CrCP by linear regression analysis. The relative changes in CrCP induced by hemodynamic challenges remained a relevant indicator of cerebrovascular regulation regardless of the methods used for non-invasive BP recording.
| Original language | English |
|---|---|
| Pages (from-to) | 369-375 |
| Number of pages | 7 |
| Journal | Cerebrovascular Diseases |
| Volume | 19 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Jul 13 2005 |
| Externally published | Yes |
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Keywords
- Carbon dioxide
- Carotid arteries
- Cerebrovascular circulation
- Critical closing pressure
- Doppler, transcranial
- Plethysmography
- Tonometry
- Ultrasonography
ASJC Scopus subject areas
- Neurology
- Clinical Neurology
- Cardiology and Cardiovascular Medicine
Cite this
Comparison of critical closing pressures extracted from carotid tonometry and finger plethysmography. / Hsu, Hung Yi; Chao, A. Ching; Chen, Ying Tsung; Wong, Wen Jang; Chern, Chang Ming; Hsu, Li Chi; Kuo, Jon Son; Hu, Han Hwa.
In: Cerebrovascular Diseases, Vol. 19, No. 6, 13.07.2005, p. 369-375.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Comparison of critical closing pressures extracted from carotid tonometry and finger plethysmography
AU - Hsu, Hung Yi
AU - Chao, A. Ching
AU - Chen, Ying Tsung
AU - Wong, Wen Jang
AU - Chern, Chang Ming
AU - Hsu, Li Chi
AU - Kuo, Jon Son
AU - Hu, Han Hwa
PY - 2005/7/13
Y1 - 2005/7/13
N2 - Background: The reliability of critical closing pressure (CrCP) estimates derived from peripheral blood pressure (BP) measurements is unclear. We attempted to evaluate the influences of peripheral circulation on determining CrCP. Methods: Twenty-five young healthy volunteers were studied. BP waves were obtained with plethysmography (Portapres) and carotid applanatory tonometry, respectively, for analysis. Transcranial Doppler was used to monitor cerebral flowvelocity. Using linear regression analysis, beat-to-beat CrCP was calculated at rest, during voluntary hyperventilation and during 5% CO2 inhalation. Results: Twenty of 25 participants demonstrating satisfactory tonometric tracings for both tests were included in the analysis. The systolic BP measured using plethysmography was higher than that derived from tonometry (139.4 ± 24.7 vs. 105.5 ± 29.6, p < 0.001). CrCP values derived from tonometry were all positive and higher than CrCP values derived from plethysmography (62.9 ± 19.9 vs. 11.1 ± 17.8, p < 0.001). The changes in CrCP induced by 5% CO2 inhalation and hyperventilation had a correlation between two BP monitoring methods (r = 0.52, p = 0.001). Conclusions: Pressure waveform is an important determinant in calculating CrCP by linear regression analysis. The relative changes in CrCP induced by hemodynamic challenges remained a relevant indicator of cerebrovascular regulation regardless of the methods used for non-invasive BP recording.
AB - Background: The reliability of critical closing pressure (CrCP) estimates derived from peripheral blood pressure (BP) measurements is unclear. We attempted to evaluate the influences of peripheral circulation on determining CrCP. Methods: Twenty-five young healthy volunteers were studied. BP waves were obtained with plethysmography (Portapres) and carotid applanatory tonometry, respectively, for analysis. Transcranial Doppler was used to monitor cerebral flowvelocity. Using linear regression analysis, beat-to-beat CrCP was calculated at rest, during voluntary hyperventilation and during 5% CO2 inhalation. Results: Twenty of 25 participants demonstrating satisfactory tonometric tracings for both tests were included in the analysis. The systolic BP measured using plethysmography was higher than that derived from tonometry (139.4 ± 24.7 vs. 105.5 ± 29.6, p < 0.001). CrCP values derived from tonometry were all positive and higher than CrCP values derived from plethysmography (62.9 ± 19.9 vs. 11.1 ± 17.8, p < 0.001). The changes in CrCP induced by 5% CO2 inhalation and hyperventilation had a correlation between two BP monitoring methods (r = 0.52, p = 0.001). Conclusions: Pressure waveform is an important determinant in calculating CrCP by linear regression analysis. The relative changes in CrCP induced by hemodynamic challenges remained a relevant indicator of cerebrovascular regulation regardless of the methods used for non-invasive BP recording.
KW - Carbon dioxide
KW - Carotid arteries
KW - Cerebrovascular circulation
KW - Critical closing pressure
KW - Doppler, transcranial
KW - Plethysmography
KW - Tonometry
KW - Ultrasonography
UR - http://www.scopus.com/inward/record.url?scp=21344436411&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=21344436411&partnerID=8YFLogxK
U2 - 10.1159/000085204
DO - 10.1159/000085204
M3 - Article
C2 - 15838164
AN - SCOPUS:21344436411
VL - 19
SP - 369
EP - 375
JO - Cerebrovascular Diseases
JF - Cerebrovascular Diseases
SN - 1015-9770
IS - 6
ER -