Comparison of critical closing pressures extracted from carotid tonometry and finger plethysmography

Hung Yi Hsu, A. Ching Chao, Ying Tsung Chen, Wen Jang Wong, Chang Ming Chern, Li Chi Hsu, Jon Son Kuo, Han Hwa Hu

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: The reliability of critical closing pressure (CrCP) estimates derived from peripheral blood pressure (BP) measurements is unclear. We attempted to evaluate the influences of peripheral circulation on determining CrCP. Methods: Twenty-five young healthy volunteers were studied. BP waves were obtained with plethysmography (Portapres) and carotid applanatory tonometry, respectively, for analysis. Transcranial Doppler was used to monitor cerebral flowvelocity. Using linear regression analysis, beat-to-beat CrCP was calculated at rest, during voluntary hyperventilation and during 5% CO2 inhalation. Results: Twenty of 25 participants demonstrating satisfactory tonometric tracings for both tests were included in the analysis. The systolic BP measured using plethysmography was higher than that derived from tonometry (139.4 ± 24.7 vs. 105.5 ± 29.6, p < 0.001). CrCP values derived from tonometry were all positive and higher than CrCP values derived from plethysmography (62.9 ± 19.9 vs. 11.1 ± 17.8, p < 0.001). The changes in CrCP induced by 5% CO2 inhalation and hyperventilation had a correlation between two BP monitoring methods (r = 0.52, p = 0.001). Conclusions: Pressure waveform is an important determinant in calculating CrCP by linear regression analysis. The relative changes in CrCP induced by hemodynamic challenges remained a relevant indicator of cerebrovascular regulation regardless of the methods used for non-invasive BP recording.

Original languageEnglish
Pages (from-to)369-375
Number of pages7
JournalCerebrovascular Diseases
Volume19
Issue number6
DOIs
Publication statusPublished - Jul 13 2005
Externally publishedYes

Fingerprint

Plethysmography
Manometry
Fingers
Pressure
Blood Pressure
Hyperventilation
Inhalation
Linear Models
Regression Analysis
Healthy Volunteers
Hemodynamics

Keywords

  • Carbon dioxide
  • Carotid arteries
  • Cerebrovascular circulation
  • Critical closing pressure
  • Doppler, transcranial
  • Plethysmography
  • Tonometry
  • Ultrasonography

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

Cite this

Comparison of critical closing pressures extracted from carotid tonometry and finger plethysmography. / Hsu, Hung Yi; Chao, A. Ching; Chen, Ying Tsung; Wong, Wen Jang; Chern, Chang Ming; Hsu, Li Chi; Kuo, Jon Son; Hu, Han Hwa.

In: Cerebrovascular Diseases, Vol. 19, No. 6, 13.07.2005, p. 369-375.

Research output: Contribution to journalArticle

Hsu, Hung Yi ; Chao, A. Ching ; Chen, Ying Tsung ; Wong, Wen Jang ; Chern, Chang Ming ; Hsu, Li Chi ; Kuo, Jon Son ; Hu, Han Hwa. / Comparison of critical closing pressures extracted from carotid tonometry and finger plethysmography. In: Cerebrovascular Diseases. 2005 ; Vol. 19, No. 6. pp. 369-375.
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