Comparison of 3 risk estimation methods for predicting cardiac outcomes in pregnant women with congenital heart disease

Chun Wei Lu, Jin Chung Shih, Ssu Yuan Chen, Hsin Hui Chiu, Jou Kou Wang, Chun An Chen, Shuenn Nan Chiu, Ming Tai Lin, Chien Nan Lee, Mei Hwan Wu

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Background: Three risk estimation methods for predicting the cardiac outcomes of pregnancy in women with heart disease have been proposed. This study was designed to compare their prediction performance in an Asian cohort with congenital heart disease (CHD). Methods and Results: This study enrolled pregnant women with CHD who delivered their babies after the 20th gestational week between 1985 and 2011. Of 268 pregnancies in 190 women with CHD, 18 (6.7%) had cardiac complications. The incidence of maternal cardiac events among women with a CARPREG index of 0, 1 or 2 was 3.4%, 27.3% and 100%. The incidence was 2.7%, 8.6%, 11.1%, 40% and 17.6% for those with a ZAHARA score 0–0.5, 0.51–1.5, 1.51–2.5, 2.51–3.5 and >3.5. Among patients with a modified World Health Organization (WHO) classification I, II, III and IV, the incidence of maternal cardiac events was 0%, 4.0%, 12.2% and 25.7%. The c-statistic was 0.732 (95% confidence interval (CI): 0.589, 0.876; P

Original languageEnglish
Pages (from-to)1609-1617
Number of pages9
JournalCirculation Journal
Volume79
Issue number7
DOIs
Publication statusPublished - Jun 9 2015
Externally publishedYes

Fingerprint

Pregnant Women
Heart Diseases
Incidence
Mothers
Pregnancy Outcome
Confidence Intervals
Pregnancy

Keywords

  • Congenital heart disease
  • Pregnancy
  • Prognosis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Lu, C. W., Shih, J. C., Chen, S. Y., Chiu, H. H., Wang, J. K., Chen, C. A., ... Wu, M. H. (2015). Comparison of 3 risk estimation methods for predicting cardiac outcomes in pregnant women with congenital heart disease. Circulation Journal, 79(7), 1609-1617. https://doi.org/10.1253/circj.CJ-14-1368

Comparison of 3 risk estimation methods for predicting cardiac outcomes in pregnant women with congenital heart disease. / Lu, Chun Wei; Shih, Jin Chung; Chen, Ssu Yuan; Chiu, Hsin Hui; Wang, Jou Kou; Chen, Chun An; Chiu, Shuenn Nan; Lin, Ming Tai; Lee, Chien Nan; Wu, Mei Hwan.

In: Circulation Journal, Vol. 79, No. 7, 09.06.2015, p. 1609-1617.

Research output: Contribution to journalArticle

Lu, CW, Shih, JC, Chen, SY, Chiu, HH, Wang, JK, Chen, CA, Chiu, SN, Lin, MT, Lee, CN & Wu, MH 2015, 'Comparison of 3 risk estimation methods for predicting cardiac outcomes in pregnant women with congenital heart disease', Circulation Journal, vol. 79, no. 7, pp. 1609-1617. https://doi.org/10.1253/circj.CJ-14-1368
Lu, Chun Wei ; Shih, Jin Chung ; Chen, Ssu Yuan ; Chiu, Hsin Hui ; Wang, Jou Kou ; Chen, Chun An ; Chiu, Shuenn Nan ; Lin, Ming Tai ; Lee, Chien Nan ; Wu, Mei Hwan. / Comparison of 3 risk estimation methods for predicting cardiac outcomes in pregnant women with congenital heart disease. In: Circulation Journal. 2015 ; Vol. 79, No. 7. pp. 1609-1617.
@article{890ba06dac68434184859de0e5acefc3,
title = "Comparison of 3 risk estimation methods for predicting cardiac outcomes in pregnant women with congenital heart disease",
abstract = "Background: Three risk estimation methods for predicting the cardiac outcomes of pregnancy in women with heart disease have been proposed. This study was designed to compare their prediction performance in an Asian cohort with congenital heart disease (CHD). Methods and Results: This study enrolled pregnant women with CHD who delivered their babies after the 20th gestational week between 1985 and 2011. Of 268 pregnancies in 190 women with CHD, 18 (6.7{\%}) had cardiac complications. The incidence of maternal cardiac events among women with a CARPREG index of 0, 1 or 2 was 3.4{\%}, 27.3{\%} and 100{\%}. The incidence was 2.7{\%}, 8.6{\%}, 11.1{\%}, 40{\%} and 17.6{\%} for those with a ZAHARA score 0–0.5, 0.51–1.5, 1.51–2.5, 2.51–3.5 and >3.5. Among patients with a modified World Health Organization (WHO) classification I, II, III and IV, the incidence of maternal cardiac events was 0{\%}, 4.0{\%}, 12.2{\%} and 25.7{\%}. The c-statistic was 0.732 (95{\%} confidence interval (CI): 0.589, 0.876; P",
keywords = "Congenital heart disease, Pregnancy, Prognosis",
author = "Lu, {Chun Wei} and Shih, {Jin Chung} and Chen, {Ssu Yuan} and Chiu, {Hsin Hui} and Wang, {Jou Kou} and Chen, {Chun An} and Chiu, {Shuenn Nan} and Lin, {Ming Tai} and Lee, {Chien Nan} and Wu, {Mei Hwan}",
year = "2015",
month = "6",
day = "9",
doi = "10.1253/circj.CJ-14-1368",
language = "English",
volume = "79",
pages = "1609--1617",
journal = "Circulation Journal",
issn = "1346-9843",
publisher = "Japanese Circulation Society",
number = "7",

}

TY - JOUR

T1 - Comparison of 3 risk estimation methods for predicting cardiac outcomes in pregnant women with congenital heart disease

AU - Lu, Chun Wei

AU - Shih, Jin Chung

AU - Chen, Ssu Yuan

AU - Chiu, Hsin Hui

AU - Wang, Jou Kou

AU - Chen, Chun An

AU - Chiu, Shuenn Nan

AU - Lin, Ming Tai

AU - Lee, Chien Nan

AU - Wu, Mei Hwan

PY - 2015/6/9

Y1 - 2015/6/9

N2 - Background: Three risk estimation methods for predicting the cardiac outcomes of pregnancy in women with heart disease have been proposed. This study was designed to compare their prediction performance in an Asian cohort with congenital heart disease (CHD). Methods and Results: This study enrolled pregnant women with CHD who delivered their babies after the 20th gestational week between 1985 and 2011. Of 268 pregnancies in 190 women with CHD, 18 (6.7%) had cardiac complications. The incidence of maternal cardiac events among women with a CARPREG index of 0, 1 or 2 was 3.4%, 27.3% and 100%. The incidence was 2.7%, 8.6%, 11.1%, 40% and 17.6% for those with a ZAHARA score 0–0.5, 0.51–1.5, 1.51–2.5, 2.51–3.5 and >3.5. Among patients with a modified World Health Organization (WHO) classification I, II, III and IV, the incidence of maternal cardiac events was 0%, 4.0%, 12.2% and 25.7%. The c-statistic was 0.732 (95% confidence interval (CI): 0.589, 0.876; P

AB - Background: Three risk estimation methods for predicting the cardiac outcomes of pregnancy in women with heart disease have been proposed. This study was designed to compare their prediction performance in an Asian cohort with congenital heart disease (CHD). Methods and Results: This study enrolled pregnant women with CHD who delivered their babies after the 20th gestational week between 1985 and 2011. Of 268 pregnancies in 190 women with CHD, 18 (6.7%) had cardiac complications. The incidence of maternal cardiac events among women with a CARPREG index of 0, 1 or 2 was 3.4%, 27.3% and 100%. The incidence was 2.7%, 8.6%, 11.1%, 40% and 17.6% for those with a ZAHARA score 0–0.5, 0.51–1.5, 1.51–2.5, 2.51–3.5 and >3.5. Among patients with a modified World Health Organization (WHO) classification I, II, III and IV, the incidence of maternal cardiac events was 0%, 4.0%, 12.2% and 25.7%. The c-statistic was 0.732 (95% confidence interval (CI): 0.589, 0.876; P

KW - Congenital heart disease

KW - Pregnancy

KW - Prognosis

UR - http://www.scopus.com/inward/record.url?scp=84934296798&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84934296798&partnerID=8YFLogxK

U2 - 10.1253/circj.CJ-14-1368

DO - 10.1253/circj.CJ-14-1368

M3 - Article

C2 - 25959432

AN - SCOPUS:84934296798

VL - 79

SP - 1609

EP - 1617

JO - Circulation Journal

JF - Circulation Journal

SN - 1346-9843

IS - 7

ER -