Comparing the effectiveness of Q-switched Ruby laser treatment with that of Q-switched Nd

YAG laser for oculodermal melanosis (Nevus of Ota)

Cheng Jen Chang, Ching Song Kou

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Background and objective: The objective of this study was to compare the efficacy and safety of Q-switched Ruby laser versus Q-switched neodymium:yttrium-aluminium-garnet (Nd:YAG) laser for oculodermal melanosis (Nevus of Ota) birthmarks in a large group of patients. Study design/Materials and methods: A retrospective review was conducted of 94 patients with Nevus of Ota treated with a Q-switched Ruby laser and a Q-switched Nd:YAG laser over a 3-year period. The subjects' ages ranged from 3 to 64 years; there were 70 females and 24 males, all of whom were of Asian descent. The number of treatments ranged from 1 to 8. Duration of treatment ranged from 6 months to 3 years and 10 months, with a mean of 14 months. Patients (n = 47) received Q-switched Ruby laser treatment (694 nm) using light dosages of 7-10 J cm -2. Subsequent patients (n = 47) received Q-switched Nd:YAG laser treatment (1064 nm) using light dosages of 7-10 J cm-2. The primary efficacy measurement was the quantitative assessment of clearing and fading response using the DermaSpectrometer for the Q-switched Ruby laser group versus the Q-switched Nd:YAG laser group. Results: Based on a paired t-test, clinical and statistically significant differences in clearing and fading response were observed amongst the Q-switched Ruby laser-treated subjects as preferred to the appearance of Q-switched Nd:YAG laser-treated group (P < 0.05). In both groups, transient hyperpigmentation resolved in all subjects within 6 months. Permanent hyperpigmentation or scarring was not observed in either group. Conclusion: Use of a Q-switched Ruby laser resulted in better clearing and fading as compared with Q-switched Nd:YAG laser.

Original languageEnglish
Pages (from-to)339-345
Number of pages7
JournalJournal of Plastic, Reconstructive and Aesthetic Surgery
Volume64
Issue number3
DOIs
Publication statusPublished - Mar 2011
Externally publishedYes

Fingerprint

Nevus of Ota
Melanosis
Solid-State Lasers
Lasers
Neodymium
Therapeutics
Hyperpigmentation
Light

Keywords

  • DermaSpectrometer
  • Nevus of Ota
  • Q-switched Nd:YAG laser
  • Q-switched Ruby laser

ASJC Scopus subject areas

  • Surgery

Cite this

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title = "Comparing the effectiveness of Q-switched Ruby laser treatment with that of Q-switched Nd: YAG laser for oculodermal melanosis (Nevus of Ota)",
abstract = "Background and objective: The objective of this study was to compare the efficacy and safety of Q-switched Ruby laser versus Q-switched neodymium:yttrium-aluminium-garnet (Nd:YAG) laser for oculodermal melanosis (Nevus of Ota) birthmarks in a large group of patients. Study design/Materials and methods: A retrospective review was conducted of 94 patients with Nevus of Ota treated with a Q-switched Ruby laser and a Q-switched Nd:YAG laser over a 3-year period. The subjects' ages ranged from 3 to 64 years; there were 70 females and 24 males, all of whom were of Asian descent. The number of treatments ranged from 1 to 8. Duration of treatment ranged from 6 months to 3 years and 10 months, with a mean of 14 months. Patients (n = 47) received Q-switched Ruby laser treatment (694 nm) using light dosages of 7-10 J cm -2. Subsequent patients (n = 47) received Q-switched Nd:YAG laser treatment (1064 nm) using light dosages of 7-10 J cm-2. The primary efficacy measurement was the quantitative assessment of clearing and fading response using the DermaSpectrometer for the Q-switched Ruby laser group versus the Q-switched Nd:YAG laser group. Results: Based on a paired t-test, clinical and statistically significant differences in clearing and fading response were observed amongst the Q-switched Ruby laser-treated subjects as preferred to the appearance of Q-switched Nd:YAG laser-treated group (P < 0.05). In both groups, transient hyperpigmentation resolved in all subjects within 6 months. Permanent hyperpigmentation or scarring was not observed in either group. Conclusion: Use of a Q-switched Ruby laser resulted in better clearing and fading as compared with Q-switched Nd:YAG laser.",
keywords = "DermaSpectrometer, Nevus of Ota, Q-switched Nd:YAG laser, Q-switched Ruby laser",
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AB - Background and objective: The objective of this study was to compare the efficacy and safety of Q-switched Ruby laser versus Q-switched neodymium:yttrium-aluminium-garnet (Nd:YAG) laser for oculodermal melanosis (Nevus of Ota) birthmarks in a large group of patients. Study design/Materials and methods: A retrospective review was conducted of 94 patients with Nevus of Ota treated with a Q-switched Ruby laser and a Q-switched Nd:YAG laser over a 3-year period. The subjects' ages ranged from 3 to 64 years; there were 70 females and 24 males, all of whom were of Asian descent. The number of treatments ranged from 1 to 8. Duration of treatment ranged from 6 months to 3 years and 10 months, with a mean of 14 months. Patients (n = 47) received Q-switched Ruby laser treatment (694 nm) using light dosages of 7-10 J cm -2. Subsequent patients (n = 47) received Q-switched Nd:YAG laser treatment (1064 nm) using light dosages of 7-10 J cm-2. The primary efficacy measurement was the quantitative assessment of clearing and fading response using the DermaSpectrometer for the Q-switched Ruby laser group versus the Q-switched Nd:YAG laser group. Results: Based on a paired t-test, clinical and statistically significant differences in clearing and fading response were observed amongst the Q-switched Ruby laser-treated subjects as preferred to the appearance of Q-switched Nd:YAG laser-treated group (P < 0.05). In both groups, transient hyperpigmentation resolved in all subjects within 6 months. Permanent hyperpigmentation or scarring was not observed in either group. Conclusion: Use of a Q-switched Ruby laser resulted in better clearing and fading as compared with Q-switched Nd:YAG laser.

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