Abstract

A bicalcium phosphate (BCP) bioceramic comprising α-tricalcium phosphate (α-TCP) and hydroxyapatite (HA) was prepared by a two-step sintering. The microstructure of the BCP bioceramic was investigated using scanning electron microscopy (SEM), transmission electron microscopy (TEM), and X-ray diffraction. The in vitro osteoinductivity was evaluated by culturing MG63 osteoblast-like cells on the BCP bioceramic. Results showed that the BCP bioceramic comprising α-TCP and HA in a moderate ratio possessed a hardness of 93.7 Hv. The cells spread faster on the BCP bioceramic than those on the commercial HA. It suggested that the BCP bioceramic can enhance osteoinductivity in vivo.

Original languageEnglish
Pages (from-to)192-198
Number of pages7
JournalInternational Journal of Applied Ceramic Technology
Volume12
Issue number1
DOIs
Publication statusPublished - Jan 1 2015

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Bioceramics
Durapatite
Hydroxyapatite
phosphates
Phosphates
Osteoblasts
osteoblasts
Electron microscopy
Microstructure
Scanning electron microscopy
X-ray diffraction
cells
Sintering
Hardness
sintering
Transmission electron microscopy
hardness
X ray diffraction
transmission electron microscopy
microstructure

ASJC Scopus subject areas

  • Ceramics and Composites
  • Marketing
  • Materials Chemistry
  • Condensed Matter Physics

Cite this

Comparative in vitro osteoinductivity study of HA and α-TCP/HA bicalcium phosphate. / Chan, Yu Hao; Chang, Yushan Sophie; Shen, Yun-Dun; Yang, Tzu Sen; Ou, Shih Fu; Hsu, Ya Ju; Huang, Mao Suan; Ou, Keng Liang.

In: International Journal of Applied Ceramic Technology, Vol. 12, No. 1, 01.01.2015, p. 192-198.

Research output: Contribution to journalArticle

Chan, Yu Hao ; Chang, Yushan Sophie ; Shen, Yun-Dun ; Yang, Tzu Sen ; Ou, Shih Fu ; Hsu, Ya Ju ; Huang, Mao Suan ; Ou, Keng Liang. / Comparative in vitro osteoinductivity study of HA and α-TCP/HA bicalcium phosphate. In: International Journal of Applied Ceramic Technology. 2015 ; Vol. 12, No. 1. pp. 192-198.
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