Comparative evaluation of stretch and non-stretch polytetrafluorethylene (PTFE) prosthetic grafts for femoro-popliteal bypass

Chorng Horng Lu, Jason Chang, Shiau Ting Lai, Chun Che Shih

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background. The results of femoropopliteal bypass surgery using various prosthetic materials are frustrated until the expanded polytetrafluorethylene (PTFE) was introduced as a vascular prosthesis in 1973. Since then, the techniques of femoropopliteal bypass improved rapidly, but the long-term patency rate, compaired with autogenous saphenous vein graft, remained unsatisfied. The stretch PTFE graft developed in 1991 became available for clinical usage. The objective of this study is to compare the long-term results between stretch and non-stretch PTFE prosthetic conduits in patients who underwent femoropopliteal vascular reconstruction. Methods. From Jun. 1993 to Jun. 1998, 68 femoropopliteal bypass operations were performed in 59 patients between stretch and non-stretch PTFE conduits. The stretch PTFE group included 34 patients, 40 surgery (above knee 22, below knee 18). The non-stretch PTFE group included 25 patients, 28 surgery (above knee 17, below knee 11). The patency of grafts was followed by Doppler segmental pressure for at least 2 years. The indication for the bypass grafting operation was disabling claudication and critical ischemia. Patients were observed every 3 months for the first year and every 6 months thereafter. All patients were instructed to take aspirin (100 mg) daily in the whole period of study. Doppler-derived ankle-brachial indices (ABIs) were determined preoperatively and serially postoperatively. A bypass graft was considered to be patent when the Doppler-derived postoperative ABI remained significantly improved (more than 0.15 units higher than their preoperative value). Patency rates were compared by using the Kaplan-Meier life table analysis. Results. Reconstructions above knee had significantly different patency rates (83% vs 66%, p < 0.05): the stretch PTFE group had more acceptable clinical result than the non-stretch PTFE group. Below-knee bypass made no significantly different results between groups, (59% vs 53%, p > 0.10). Conclusions. The stretch PTFE stretches farer and makes better long-term patency for femoropopliteal bypass. We suggested that the stretch PTFE prosthetic conduits is a reasonable alternative for the above knee popliteal artery lesions and reserved for patients lacking autogenous tissues for below knee artery reconstruction.

Original languageEnglish
Pages (from-to)200-204
Number of pages5
JournalChinese Medical Journal (Taipei)
Volume65
Issue number5
Publication statusPublished - Aug 7 2002
Externally publishedYes

Fingerprint

Knee
Transplants
Ankle Brachial Index
Blood Vessel Prosthesis
Popliteal Artery
Life Tables
Saphenous Vein
Aspirin
Blood Vessels
Ischemia
Arteries
Pressure

Keywords

  • Blood vessel prosthesis
  • Femoropopliteal bypass
  • Polytetrafluorethylene

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Comparative evaluation of stretch and non-stretch polytetrafluorethylene (PTFE) prosthetic grafts for femoro-popliteal bypass. / Lu, Chorng Horng; Chang, Jason; Lai, Shiau Ting; Shih, Chun Che.

In: Chinese Medical Journal (Taipei), Vol. 65, No. 5, 07.08.2002, p. 200-204.

Research output: Contribution to journalArticle

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abstract = "Background. The results of femoropopliteal bypass surgery using various prosthetic materials are frustrated until the expanded polytetrafluorethylene (PTFE) was introduced as a vascular prosthesis in 1973. Since then, the techniques of femoropopliteal bypass improved rapidly, but the long-term patency rate, compaired with autogenous saphenous vein graft, remained unsatisfied. The stretch PTFE graft developed in 1991 became available for clinical usage. The objective of this study is to compare the long-term results between stretch and non-stretch PTFE prosthetic conduits in patients who underwent femoropopliteal vascular reconstruction. Methods. From Jun. 1993 to Jun. 1998, 68 femoropopliteal bypass operations were performed in 59 patients between stretch and non-stretch PTFE conduits. The stretch PTFE group included 34 patients, 40 surgery (above knee 22, below knee 18). The non-stretch PTFE group included 25 patients, 28 surgery (above knee 17, below knee 11). The patency of grafts was followed by Doppler segmental pressure for at least 2 years. The indication for the bypass grafting operation was disabling claudication and critical ischemia. Patients were observed every 3 months for the first year and every 6 months thereafter. All patients were instructed to take aspirin (100 mg) daily in the whole period of study. Doppler-derived ankle-brachial indices (ABIs) were determined preoperatively and serially postoperatively. A bypass graft was considered to be patent when the Doppler-derived postoperative ABI remained significantly improved (more than 0.15 units higher than their preoperative value). Patency rates were compared by using the Kaplan-Meier life table analysis. Results. Reconstructions above knee had significantly different patency rates (83{\%} vs 66{\%}, p < 0.05): the stretch PTFE group had more acceptable clinical result than the non-stretch PTFE group. Below-knee bypass made no significantly different results between groups, (59{\%} vs 53{\%}, p > 0.10). Conclusions. The stretch PTFE stretches farer and makes better long-term patency for femoropopliteal bypass. We suggested that the stretch PTFE prosthetic conduits is a reasonable alternative for the above knee popliteal artery lesions and reserved for patients lacking autogenous tissues for below knee artery reconstruction.",
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AU - Shih, Chun Che

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N2 - Background. The results of femoropopliteal bypass surgery using various prosthetic materials are frustrated until the expanded polytetrafluorethylene (PTFE) was introduced as a vascular prosthesis in 1973. Since then, the techniques of femoropopliteal bypass improved rapidly, but the long-term patency rate, compaired with autogenous saphenous vein graft, remained unsatisfied. The stretch PTFE graft developed in 1991 became available for clinical usage. The objective of this study is to compare the long-term results between stretch and non-stretch PTFE prosthetic conduits in patients who underwent femoropopliteal vascular reconstruction. Methods. From Jun. 1993 to Jun. 1998, 68 femoropopliteal bypass operations were performed in 59 patients between stretch and non-stretch PTFE conduits. The stretch PTFE group included 34 patients, 40 surgery (above knee 22, below knee 18). The non-stretch PTFE group included 25 patients, 28 surgery (above knee 17, below knee 11). The patency of grafts was followed by Doppler segmental pressure for at least 2 years. The indication for the bypass grafting operation was disabling claudication and critical ischemia. Patients were observed every 3 months for the first year and every 6 months thereafter. All patients were instructed to take aspirin (100 mg) daily in the whole period of study. Doppler-derived ankle-brachial indices (ABIs) were determined preoperatively and serially postoperatively. A bypass graft was considered to be patent when the Doppler-derived postoperative ABI remained significantly improved (more than 0.15 units higher than their preoperative value). Patency rates were compared by using the Kaplan-Meier life table analysis. Results. Reconstructions above knee had significantly different patency rates (83% vs 66%, p < 0.05): the stretch PTFE group had more acceptable clinical result than the non-stretch PTFE group. Below-knee bypass made no significantly different results between groups, (59% vs 53%, p > 0.10). Conclusions. The stretch PTFE stretches farer and makes better long-term patency for femoropopliteal bypass. We suggested that the stretch PTFE prosthetic conduits is a reasonable alternative for the above knee popliteal artery lesions and reserved for patients lacking autogenous tissues for below knee artery reconstruction.

AB - Background. The results of femoropopliteal bypass surgery using various prosthetic materials are frustrated until the expanded polytetrafluorethylene (PTFE) was introduced as a vascular prosthesis in 1973. Since then, the techniques of femoropopliteal bypass improved rapidly, but the long-term patency rate, compaired with autogenous saphenous vein graft, remained unsatisfied. The stretch PTFE graft developed in 1991 became available for clinical usage. The objective of this study is to compare the long-term results between stretch and non-stretch PTFE prosthetic conduits in patients who underwent femoropopliteal vascular reconstruction. Methods. From Jun. 1993 to Jun. 1998, 68 femoropopliteal bypass operations were performed in 59 patients between stretch and non-stretch PTFE conduits. The stretch PTFE group included 34 patients, 40 surgery (above knee 22, below knee 18). The non-stretch PTFE group included 25 patients, 28 surgery (above knee 17, below knee 11). The patency of grafts was followed by Doppler segmental pressure for at least 2 years. The indication for the bypass grafting operation was disabling claudication and critical ischemia. Patients were observed every 3 months for the first year and every 6 months thereafter. All patients were instructed to take aspirin (100 mg) daily in the whole period of study. Doppler-derived ankle-brachial indices (ABIs) were determined preoperatively and serially postoperatively. A bypass graft was considered to be patent when the Doppler-derived postoperative ABI remained significantly improved (more than 0.15 units higher than their preoperative value). Patency rates were compared by using the Kaplan-Meier life table analysis. Results. Reconstructions above knee had significantly different patency rates (83% vs 66%, p < 0.05): the stretch PTFE group had more acceptable clinical result than the non-stretch PTFE group. Below-knee bypass made no significantly different results between groups, (59% vs 53%, p > 0.10). Conclusions. The stretch PTFE stretches farer and makes better long-term patency for femoropopliteal bypass. We suggested that the stretch PTFE prosthetic conduits is a reasonable alternative for the above knee popliteal artery lesions and reserved for patients lacking autogenous tissues for below knee artery reconstruction.

KW - Blood vessel prosthesis

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