Comorbidity profile of chronic rhinosinusitis: A population-based study

Shiu Dong Chung, Po Yueh Chen, Herng Ching Lin, Shih Han Hung

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Objectives/Hypothesis This study aimed to explore the prevalence of a broad spectrum of comorbid medical conditions among patients with chronic rhinosinusitis (CRS), using a population-based dataset. Study design A cross-sectional study. Methods In total, 5,734 CRS subjects and 17,202 comparison subjects were included in this study. Separate conditional logistic regression analyses were performed to calculate the odds ratio (OR) for each of 39 medical comorbidities between subjects with and without CRS. Results For 27 of the 39 study comorbidities, results showed that subjects with CRS had a statistically significantly higher OR than subjects without CRS after adjusting for sociodemographic characteristics. Ranks of the top five comorbid relationships from the strongest ORs to the lowest were as follows: asthma (OR=3.09), chronic pulmonary disease (OR=3.04), weight loss (OR=2.58), obesity (OR=2.50), and migraines (OR=2.30). Conclusion Our results indicate that subjects with CRS have an increased prevalence of various comorbidities. Level of Evidence 3b. Laryngoscope, 124:1536-1541, 2014

Original languageEnglish
Pages (from-to)1536-1541
Number of pages6
JournalLaryngoscope
Volume124
Issue number7
DOIs
Publication statusPublished - 2014

Fingerprint

Comorbidity
Odds Ratio
Population
Laryngoscopes
Migraine Disorders
Lung Diseases
Weight Loss
Chronic Disease
Asthma
Obesity
Cross-Sectional Studies
Logistic Models
Regression Analysis

Keywords

  • Chronic rhinosinusitis
  • comorbidity

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Comorbidity profile of chronic rhinosinusitis : A population-based study. / Chung, Shiu Dong; Chen, Po Yueh; Lin, Herng Ching; Hung, Shih Han.

In: Laryngoscope, Vol. 124, No. 7, 2014, p. 1536-1541.

Research output: Contribution to journalArticle

Chung, Shiu Dong ; Chen, Po Yueh ; Lin, Herng Ching ; Hung, Shih Han. / Comorbidity profile of chronic rhinosinusitis : A population-based study. In: Laryngoscope. 2014 ; Vol. 124, No. 7. pp. 1536-1541.
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