Comorbid diseases as risk factors for incident posttraumatic stress disorder (PTSD) in a large community cohort (KCIS no.PSY4)

Jung Chen Chang, Amy Ming Fang Yen, Hsiu Hsi Chen, Sam Li Sheng Chen, Sherry Yueh Hsia Chiu, Jean Ching Yuan Fann, Chau Shoun Lee

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Nature disasters and terrorist attacks have occurred globally in recent years. Posttraumatic stress disorder (PTSD) has gained increasing attention, but its incidence and comorbidities in the general population are different from those inside the disaster areas. The present study estimated incident PTSD and comorbid diseases for over a decade in a cohort from a community-based integrated screening program. Factors associated with the incidence of PTSD were analyzed using Cox regression models. PTSD incidence was estimated as 81 per 10 5 person-years. Incidence was higher in females than in males and one-year increments in age lowered the risk for PTSD by 3%. Adjusting for other factors, cardiovascular heart disease (adjusted hazard ratio (aHR) = 1.45, 95% confidence interval (CI): 1.03-2.04), bipolar disorder (aHR = 1.86, 95% CI: 1.07-3.24) and major depressive disorder (aHR = 7.03, 95% CI: 5.02-9.85) all significantly increased 45%, 86% and 603%, respectively, the risk of developing PTSD. The low rate of people with incident PTSD receiving treatment in this community health screening population implies there is room for improvement in terms of early detection and intervention. Clinical preventive efforts may be made for patients seeking general medical help, especially those with cardiovascular disorders or mood disorders.

Original languageEnglish
Article number41276
JournalScientific Reports
Volume7
DOIs
Publication statusPublished - Jan 27 2017

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Post-Traumatic Stress Disorders
Incidence
Disasters
Confidence Intervals
Major Depressive Disorder
Mood Disorders
Bipolar Disorder
Proportional Hazards Models
Population
Comorbidity
Heart Diseases
Cardiovascular Diseases
Health

ASJC Scopus subject areas

  • General

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Comorbid diseases as risk factors for incident posttraumatic stress disorder (PTSD) in a large community cohort (KCIS no.PSY4). / Chang, Jung Chen; Yen, Amy Ming Fang; Chen, Hsiu Hsi; Chen, Sam Li Sheng; Chiu, Sherry Yueh Hsia; Fann, Jean Ching Yuan; Lee, Chau Shoun.

In: Scientific Reports, Vol. 7, 41276, 27.01.2017.

Research output: Contribution to journalArticle

Chang, Jung Chen ; Yen, Amy Ming Fang ; Chen, Hsiu Hsi ; Chen, Sam Li Sheng ; Chiu, Sherry Yueh Hsia ; Fann, Jean Ching Yuan ; Lee, Chau Shoun. / Comorbid diseases as risk factors for incident posttraumatic stress disorder (PTSD) in a large community cohort (KCIS no.PSY4). In: Scientific Reports. 2017 ; Vol. 7.
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