Combination antipsychotic therapy in psychiatric outpatient clinics in Taiwan

Si Sheng Huang, Yi Cheng Liao, Yen Yuh Hsieh, Chin Yi Huang, Nan Ying Chiu, Yen Kuang Yang, Winston W. Shen

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Objective: The purpose of this study is to survey the use of combination antipsychotic therapy (CAT) in the psychiatric outpatient clinic of a general hospital. Methods: Patients who received at least 2 antipsychotics in the psychiatric outpatient clinic of a general hospital in 1 month (August 1-31, 2003) were identified, and their retrospective chart review was performed. Using a questionnaire, we surveyed the clinicians on why 2 antipsychotics were prescribed, why long-term CAT was used, and whether the problems were solved by CAT. Results: We studied 957 patients diagnosed with schizophrenia and related disorders in 1 month. A total of 119 patients (12%) were prescribed at least 2 antipsychotics. Among these 119 patients, 91 (76%) were prescribed 2 types of first-generation antipsychotics (FGAs), and 15 patients (16%) were prescribed a second-generation antipsychotic medication and a low-dose FGA medication. The clinicians' main reasons for CAT were to treat insomnia (84%) and psychotic symptoms (83%). Conclusions: The results of this study revealed that 12% of the patients received CAT in the clinical practice. Most patients were prescribed 2 FGAs. The clinicians' reasons for prescribing CAT in Taiwan were to treat insomnia and psychotic symptoms.

Original languageEnglish
Pages (from-to)421-425
Number of pages5
JournalComprehensive Psychiatry
Volume47
Issue number5
DOIs
Publication statusPublished - Sep 2006

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry
  • Psychology(all)

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