Cobalamin deficiency with myelopathy: MRI findings

Jerry Chin Wei Chien, Chi Tzong Hong, Wing P. Chan

Research output: Contribution to journalArticle

Abstract

We described a 61-year-old man with cobalamin deficiency presenting with thoracic myelopathy for one month. Initial T2-weighted MR images revealed abnormal symmetrical hyperintense signal at posterior column of the spinal cord between T7 and T10 levels. The vertebral bone marrow depicted abnormal hypointense signal on both T1 and T2-weighted images. Subsequent serological test confirmed cobalamin deficiency. Although only few cases have been reported, abnormal MRI findings on the spinal cord and vertebral bone marrow should alert clinicians to consider Cobalamin deficiency. Laboratory tests should be performed to confirm the diagnosis. In our case, follow-up MRI findings correlated well with clinical outcome after treatment.

Original languageEnglish
Pages (from-to)325-328
Number of pages4
JournalChinese Journal of Radiology
Volume27
Issue number6
Publication statusPublished - Dec 2002

Keywords

  • Anemia
  • Bone marrow
  • Cobalamin deficiency
  • Magnetic resonance imaging (MRI)
  • Spinal cord
  • Subacute combined degeneration
  • Vitamin B deficiency

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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