Cluster headache is associated with an increased risk of depression: A nationwide population-based cohort study

Jen Feng Liang, Yung Tai Chen, Jong Ling Fuh, Szu Yuan Li, Chia Jen Liu, Tzeng Ji Chen, Chao Hsiun Tang, Shuu Jiun Wang

Research output: Contribution to journalArticle

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Abstract

Objective: To investigate whether cluster headache (CH) was a risk factor for depression in a nationwide population-based follow-up study. Background: There are few studies about the relationship between CH and depression, and prior research has been limited by cross-sectional studies or small sample sizes. Methods: We identified 673 CH patients from the Taiwan National Health Insurance database between 2005 and 2009. The two comparison cohorts included age-, sex- and Charlsons score-matched migraine patients (n=2692) and controls (patients free from migraine or CH, n=2692). The cumulative incidence of depression was compared among these three cohorts until the end of 2009. We also calculated predictors of depression in the CH cohort. Results: After the median 2.5-year follow-up duration, the CH cohort had a greater risk for developing depression compared to the control cohort (adjusted hazard ratio; aHR=5.6, 95% CI 3.0-10.6, p

Original languageEnglish
Pages (from-to)182-189
Number of pages8
JournalCephalalgia
Volume33
Issue number3
DOIs
Publication statusPublished - Feb 2013

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Cluster Headache
Cohort Studies
Population
Migraine Disorders
National Health Programs
Taiwan
Sample Size
Cross-Sectional Studies
Databases
Incidence
Research

Keywords

  • Cluster headache
  • depression
  • incidence
  • migraine
  • risk
  • Taiwan

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Liang, J. F., Chen, Y. T., Fuh, J. L., Li, S. Y., Liu, C. J., Chen, T. J., ... Wang, S. J. (2013). Cluster headache is associated with an increased risk of depression: A nationwide population-based cohort study. Cephalalgia, 33(3), 182-189. https://doi.org/10.1177/0333102412469738

Cluster headache is associated with an increased risk of depression : A nationwide population-based cohort study. / Liang, Jen Feng; Chen, Yung Tai; Fuh, Jong Ling; Li, Szu Yuan; Liu, Chia Jen; Chen, Tzeng Ji; Tang, Chao Hsiun; Wang, Shuu Jiun.

In: Cephalalgia, Vol. 33, No. 3, 02.2013, p. 182-189.

Research output: Contribution to journalArticle

Liang, Jen Feng ; Chen, Yung Tai ; Fuh, Jong Ling ; Li, Szu Yuan ; Liu, Chia Jen ; Chen, Tzeng Ji ; Tang, Chao Hsiun ; Wang, Shuu Jiun. / Cluster headache is associated with an increased risk of depression : A nationwide population-based cohort study. In: Cephalalgia. 2013 ; Vol. 33, No. 3. pp. 182-189.
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