Purpose. Adult intussusception is a uncommon disease, and the colonic inrussusception is less than enteric intussusception. Because of the limited experience with such clinical entities, we report a series of adult colonic intussusception to discuss diagnosis and treatment. Methods. From January 1997 to December 2008, a total of 18 patients with adult colonic intussusceptions were reviewed. We divided the patients into colocolic group and ileocolic group and analyzed the data of these 18 patients. Results. There were 11 ileocolic intussusception and 7 colocolic intussusception. The mean duration of symptoms was 22.2 days (range 1 to 105 days), and abdominal pain was represented in all patients. Only one patient underwent hydrostatic reduction without operation and others underwent bowel resection with organic lesion. One hundred percent of colocolic intussusception cases were malignant lesions and this was more than ileocolic intussusceptions (27% and p＜0.001). All patients with colon cancer had a favorable outcome and are still alive. Conclusion. Colonic intussusception in adults is a rare disease. Abdominal pain is complained of by all patients but the symptoms have various duration. Abdominal ultrasonography and computed tomography are useful tools for colonic intussusception diagnosis. In our study, colocolic intussusception had more malignant probability than ileocolic intussusception. Primary resection with associated lymph node dissection without reduction is the principle method of treatment.