Clinical outcome of very late recurrence of atrial fibrillation after catheter ablation of paroxysmal atrial fibrillation

Ming Hsiung Hsieh, Ching Tai Tai, Chin Feng Tsai, Wei Shiang Lin, Yung Kuo Lin, Hsuan Ming Tsao, Jin Long Huang, Kwo Chang Ueng, Wen Chung Yu, Paul Chan, Yu An Ding, Mau Song Chang, Shih Ann Chen

Research output: Contribution to journalArticle

57 Citations (Scopus)

Abstract

Very Late Recurrence of AF. Introduction: High recurrence rate is still a major problem associated with ablation of paroxysmal atrial fibrillation (AF). Most of the recurrences occur within 6 months after ablation. The characteristics of very late recurrent AF (> 12 months after ablation) have not been reported. Methods and Results: Two hundred seven patients with drug-refractory AF underwent successful focal ablation or isolation of AF loci. After the first ablation procedure, Holter monitoring and event recorders were used to evaluate symptomatic recurrent AF. A second ablation procedure was recommended if the antiarrhythmic drugs could not control recurrent AF. During long-term follow-up (mean 30 ± 11 months, up to 51 months), 70 patients had recurrent AF, including 13 patients (6%) with very late (>12 months) recurrent AF (group 1) and 57 patients (28%) with late (within 12 months after ablation) recurrent AF(group 2). Group 1 patients had a significantly lower incidence of multiple (≥2) AF foci (23% vs 63%, P = 0.02) than group 2 patients. In addition, the incidence of antiarrhythmic drugs use (38% vs 84%, P = 0.001) to maintain sinus rhythm after the first episode of recurrent AF was significantly lower in group 1 than group 2 patients, and the incidence of a second intervention procedure (8% vs 35%, P = 0.051) tended to be lower in group 1 than group 2 patients. Conclusion: The incidence of very late recurrent AF after ablation of paroxysmal AF is very low, and the clinical outcome of patients with very late recurrent AF is benign.

Original languageEnglish
Pages (from-to)598-601
Number of pages4
JournalJournal of Cardiovascular Electrophysiology
Volume14
Issue number6
DOIs
Publication statusPublished - Jun 1 2003
Externally publishedYes

Fingerprint

Catheter Ablation
Atrial Fibrillation
Recurrence
Anti-Arrhythmia Agents
Incidence
Ambulatory Electrocardiography

Keywords

  • Paroxysmal atrial fibrillation
  • Radiofrequency catheter ablation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology

Cite this

Clinical outcome of very late recurrence of atrial fibrillation after catheter ablation of paroxysmal atrial fibrillation. / Hsieh, Ming Hsiung; Tai, Ching Tai; Tsai, Chin Feng; Lin, Wei Shiang; Lin, Yung Kuo; Tsao, Hsuan Ming; Huang, Jin Long; Ueng, Kwo Chang; Yu, Wen Chung; Chan, Paul; Ding, Yu An; Chang, Mau Song; Chen, Shih Ann.

In: Journal of Cardiovascular Electrophysiology, Vol. 14, No. 6, 01.06.2003, p. 598-601.

Research output: Contribution to journalArticle

Hsieh, Ming Hsiung ; Tai, Ching Tai ; Tsai, Chin Feng ; Lin, Wei Shiang ; Lin, Yung Kuo ; Tsao, Hsuan Ming ; Huang, Jin Long ; Ueng, Kwo Chang ; Yu, Wen Chung ; Chan, Paul ; Ding, Yu An ; Chang, Mau Song ; Chen, Shih Ann. / Clinical outcome of very late recurrence of atrial fibrillation after catheter ablation of paroxysmal atrial fibrillation. In: Journal of Cardiovascular Electrophysiology. 2003 ; Vol. 14, No. 6. pp. 598-601.
@article{edf333eb5e4d46a38a6a261cc5395976,
title = "Clinical outcome of very late recurrence of atrial fibrillation after catheter ablation of paroxysmal atrial fibrillation",
abstract = "Very Late Recurrence of AF. Introduction: High recurrence rate is still a major problem associated with ablation of paroxysmal atrial fibrillation (AF). Most of the recurrences occur within 6 months after ablation. The characteristics of very late recurrent AF (> 12 months after ablation) have not been reported. Methods and Results: Two hundred seven patients with drug-refractory AF underwent successful focal ablation or isolation of AF loci. After the first ablation procedure, Holter monitoring and event recorders were used to evaluate symptomatic recurrent AF. A second ablation procedure was recommended if the antiarrhythmic drugs could not control recurrent AF. During long-term follow-up (mean 30 ± 11 months, up to 51 months), 70 patients had recurrent AF, including 13 patients (6{\%}) with very late (>12 months) recurrent AF (group 1) and 57 patients (28{\%}) with late (within 12 months after ablation) recurrent AF(group 2). Group 1 patients had a significantly lower incidence of multiple (≥2) AF foci (23{\%} vs 63{\%}, P = 0.02) than group 2 patients. In addition, the incidence of antiarrhythmic drugs use (38{\%} vs 84{\%}, P = 0.001) to maintain sinus rhythm after the first episode of recurrent AF was significantly lower in group 1 than group 2 patients, and the incidence of a second intervention procedure (8{\%} vs 35{\%}, P = 0.051) tended to be lower in group 1 than group 2 patients. Conclusion: The incidence of very late recurrent AF after ablation of paroxysmal AF is very low, and the clinical outcome of patients with very late recurrent AF is benign.",
keywords = "Paroxysmal atrial fibrillation, Radiofrequency catheter ablation",
author = "Hsieh, {Ming Hsiung} and Tai, {Ching Tai} and Tsai, {Chin Feng} and Lin, {Wei Shiang} and Lin, {Yung Kuo} and Tsao, {Hsuan Ming} and Huang, {Jin Long} and Ueng, {Kwo Chang} and Yu, {Wen Chung} and Paul Chan and Ding, {Yu An} and Chang, {Mau Song} and Chen, {Shih Ann}",
year = "2003",
month = "6",
day = "1",
doi = "10.1046/j.1540-8167.2003.03047.x",
language = "English",
volume = "14",
pages = "598--601",
journal = "Journal of Cardiovascular Electrophysiology",
issn = "1045-3873",
publisher = "Wiley-Blackwell",
number = "6",

}

TY - JOUR

T1 - Clinical outcome of very late recurrence of atrial fibrillation after catheter ablation of paroxysmal atrial fibrillation

AU - Hsieh, Ming Hsiung

AU - Tai, Ching Tai

AU - Tsai, Chin Feng

AU - Lin, Wei Shiang

AU - Lin, Yung Kuo

AU - Tsao, Hsuan Ming

AU - Huang, Jin Long

AU - Ueng, Kwo Chang

AU - Yu, Wen Chung

AU - Chan, Paul

AU - Ding, Yu An

AU - Chang, Mau Song

AU - Chen, Shih Ann

PY - 2003/6/1

Y1 - 2003/6/1

N2 - Very Late Recurrence of AF. Introduction: High recurrence rate is still a major problem associated with ablation of paroxysmal atrial fibrillation (AF). Most of the recurrences occur within 6 months after ablation. The characteristics of very late recurrent AF (> 12 months after ablation) have not been reported. Methods and Results: Two hundred seven patients with drug-refractory AF underwent successful focal ablation or isolation of AF loci. After the first ablation procedure, Holter monitoring and event recorders were used to evaluate symptomatic recurrent AF. A second ablation procedure was recommended if the antiarrhythmic drugs could not control recurrent AF. During long-term follow-up (mean 30 ± 11 months, up to 51 months), 70 patients had recurrent AF, including 13 patients (6%) with very late (>12 months) recurrent AF (group 1) and 57 patients (28%) with late (within 12 months after ablation) recurrent AF(group 2). Group 1 patients had a significantly lower incidence of multiple (≥2) AF foci (23% vs 63%, P = 0.02) than group 2 patients. In addition, the incidence of antiarrhythmic drugs use (38% vs 84%, P = 0.001) to maintain sinus rhythm after the first episode of recurrent AF was significantly lower in group 1 than group 2 patients, and the incidence of a second intervention procedure (8% vs 35%, P = 0.051) tended to be lower in group 1 than group 2 patients. Conclusion: The incidence of very late recurrent AF after ablation of paroxysmal AF is very low, and the clinical outcome of patients with very late recurrent AF is benign.

AB - Very Late Recurrence of AF. Introduction: High recurrence rate is still a major problem associated with ablation of paroxysmal atrial fibrillation (AF). Most of the recurrences occur within 6 months after ablation. The characteristics of very late recurrent AF (> 12 months after ablation) have not been reported. Methods and Results: Two hundred seven patients with drug-refractory AF underwent successful focal ablation or isolation of AF loci. After the first ablation procedure, Holter monitoring and event recorders were used to evaluate symptomatic recurrent AF. A second ablation procedure was recommended if the antiarrhythmic drugs could not control recurrent AF. During long-term follow-up (mean 30 ± 11 months, up to 51 months), 70 patients had recurrent AF, including 13 patients (6%) with very late (>12 months) recurrent AF (group 1) and 57 patients (28%) with late (within 12 months after ablation) recurrent AF(group 2). Group 1 patients had a significantly lower incidence of multiple (≥2) AF foci (23% vs 63%, P = 0.02) than group 2 patients. In addition, the incidence of antiarrhythmic drugs use (38% vs 84%, P = 0.001) to maintain sinus rhythm after the first episode of recurrent AF was significantly lower in group 1 than group 2 patients, and the incidence of a second intervention procedure (8% vs 35%, P = 0.051) tended to be lower in group 1 than group 2 patients. Conclusion: The incidence of very late recurrent AF after ablation of paroxysmal AF is very low, and the clinical outcome of patients with very late recurrent AF is benign.

KW - Paroxysmal atrial fibrillation

KW - Radiofrequency catheter ablation

UR - http://www.scopus.com/inward/record.url?scp=0037790605&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037790605&partnerID=8YFLogxK

U2 - 10.1046/j.1540-8167.2003.03047.x

DO - 10.1046/j.1540-8167.2003.03047.x

M3 - Article

VL - 14

SP - 598

EP - 601

JO - Journal of Cardiovascular Electrophysiology

JF - Journal of Cardiovascular Electrophysiology

SN - 1045-3873

IS - 6

ER -