Clinical isolation of vancomycin-resistant Enterococcus faecalis in Taiwan

Ren J. Ben, Jang J. Lu, Tzuu Guang Young, Wei Ming Chi, Chih Chien Wang, Mong Ling Chu, Jieung Cheung Wang

Research output: Contribution to journalArticle

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Abstract

We report the isolation of a vancomycin-resistant strain of Enterococcus faecalis, designated AH803, from a 76-year-old Taiwanese woman with pneumonia and bacteremia. This is the first documented clinical isolation of a vancomycin-resistant enterococcus in Taiwan. AH803 was repeatedly isolated from sputum specimens of the patient. AH803 had a high level of vancomycin (minimal inhibitory concentration, MIC = 512 μg/mL) and gentamicin (MIC > 2,000 μg/mL) resistance, but was susceptible to teicoplanin (MIC = 8 μg/mL) and ampicillin (MIC = 2 μg/mL). AH803 was shown by polymerase chain reaction to have the vanA gene, but not the vanB gene. Despite treatment efforts, the patient's condition continued to deteriorate. She requested to be discharged, against medical advice. The patient died at home the following day after discharge.

Original languageEnglish
Pages (from-to)946-949
Number of pages4
JournalJournal of the Formosan Medical Association = Taiwan yi zhi
Volume95
Issue number12
Publication statusPublished - Dec 1996
Externally publishedYes

Fingerprint

Enterococcus faecalis
Taiwan
Teicoplanin
Vancomycin
Ampicillin
Bacteremia
Gentamicins
Sputum
Genes
Pneumonia
Polymerase Chain Reaction
Vancomycin-Resistant Enterococci
Therapeutics

Keywords

  • minimum inhibitory concentration
  • polymerase chain reaction
  • Taiwan
  • teicoplanin
  • vancomycin
  • vancomycin-resistant Enterococcus faecalis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Ben, R. J., Lu, J. J., Young, T. G., Chi, W. M., Wang, C. C., Chu, M. L., & Wang, J. C. (1996). Clinical isolation of vancomycin-resistant Enterococcus faecalis in Taiwan. Journal of the Formosan Medical Association = Taiwan yi zhi, 95(12), 946-949.

Clinical isolation of vancomycin-resistant Enterococcus faecalis in Taiwan. / Ben, Ren J.; Lu, Jang J.; Young, Tzuu Guang; Chi, Wei Ming; Wang, Chih Chien; Chu, Mong Ling; Wang, Jieung Cheung.

In: Journal of the Formosan Medical Association = Taiwan yi zhi, Vol. 95, No. 12, 12.1996, p. 946-949.

Research output: Contribution to journalArticle

Ben, RJ, Lu, JJ, Young, TG, Chi, WM, Wang, CC, Chu, ML & Wang, JC 1996, 'Clinical isolation of vancomycin-resistant Enterococcus faecalis in Taiwan', Journal of the Formosan Medical Association = Taiwan yi zhi, vol. 95, no. 12, pp. 946-949.
Ben, Ren J. ; Lu, Jang J. ; Young, Tzuu Guang ; Chi, Wei Ming ; Wang, Chih Chien ; Chu, Mong Ling ; Wang, Jieung Cheung. / Clinical isolation of vancomycin-resistant Enterococcus faecalis in Taiwan. In: Journal of the Formosan Medical Association = Taiwan yi zhi. 1996 ; Vol. 95, No. 12. pp. 946-949.
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