Clinical experience of HIV/AIDS in a municipal hospital in Taiwan.

YEN-LIN WU, Chi-Ching Chang, HANG-CHUAN CHANG, Chin Hui Yang, Say Tsung Liao

Research output: Contribution to journalArticle

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Abstract

To describe the spectrum of epidemiological and major clinical manifestations of patients infected by human immunodeficiency virus type 1 (HIV-1) in a municipal hospital, a retrospective review was done of 53 HIV-1-infected patients who had been admitted to Taipei Municipal Jen-Ai Hospital between January 1990, and July 1996. The majority (94.3%) of the patients in the cohort were male. Peak incidence was found in the fourth decade (28.3%). Forty-four (83%) patients presented in the first hospital stay with acquired immunodeficiency syndrome (AIDS). The mean duration between establishment of diagnosis of HIV-1 infection and that of AIDS was 11.2 (0-84) months. Heterosexual transmission accounted for 54.7% of the infections in the study group, and bi-/homosexual men made up another 32%. Psychosis of new onset was noted in two patients. In all AIDS indicator conditions, Pneumocystis carinii pneumonia (PCP) was the leading opportunistic infection among AIDS patients. PCP was also on the top of initial manifestations of HIV-1 infection. One patient with Penicillium marneffei infection was diagnosed to have AIDS. The mean CD4 count at admission of AIDS patients was much lower than that of non-AIDS patients (32 vs. 297/microliter, p <0.0005). During the follow-up period 24 of 53 patients died. Mean survival time of 23 expired patients after establishment of diagnosis of AIDS was 6.4 (0-29) months. The results indicated that males outnumbered females greatly in the number of cases. Sexual activity remained the most important route of infection. Psychosis of new onset may be an early manifestation of HIV-associated encephalopathy and requires more attention. In addition, the outcome was poor as most patients in this area did not become aware of risk of HIV-1 infection until they were seriously illed with full-blown AIDS that they would seek medical help. PCP was the most common incentive for medical consultation. Penicillium marneffei infection is endemic in southeast Asia, and should be classified as an AIDS indicator condition in Taiwan.

Original languageEnglish
Pages (from-to)84-95
Number of pages12
JournalZhonghua Minguo wei sheng wu ji mian yi xue za zhi = Chinese journal of microbiology and immunology
Volume30
Issue number2
Publication statusPublished - 1997
Externally publishedYes

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Municipal Hospitals
Taiwan
Acquired Immunodeficiency Syndrome
HIV
HIV-1
Pneumocystis Pneumonia
Virus Diseases
Penicillium
Infection
Psychotic Disorders
AIDS Dementia Complex
Southeastern Asia
Heterosexuality
Opportunistic Infections
CD4 Lymphocyte Count
Sexual Behavior
Motivation
Length of Stay

Cite this

Clinical experience of HIV/AIDS in a municipal hospital in Taiwan. / WU, YEN-LIN; Chang, Chi-Ching; CHANG, HANG-CHUAN ; Yang, Chin Hui; Liao, Say Tsung.

In: Zhonghua Minguo wei sheng wu ji mian yi xue za zhi = Chinese journal of microbiology and immunology, Vol. 30, No. 2, 1997, p. 84-95.

Research output: Contribution to journalArticle

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