Clinical course and computed tomography abnormalities associated without and with concomitant infection in patients with pandemic influenza A (H1N1) 2009 virus infection

Chen Ju Fu, Huan Wen Chen, Tzou Yien Lin, Yon Cheong Wong, Li Jen Wang, Yung Liang Wan, Chao Ran Wang, Chien Cheng Chen, Chung Guei Huang, Yi Kang Ku, Huan Wu Chen

Research output: Contribution to journalArticle

Abstract

The goal was to evaluate the imaging findings in patients infected primarily with the pandemic influenza A (H1N1) 2009 virus and secondarily with a bacterium. Between October 2009 and March 2010, thirteen patients were included in this study. Five patients had H1N1 pneumonia without evidence of co-infection and their CT images showed diffuse or patchy areas of ground glass opacities and/or consolidations, lower lung zone predominant, without cyst/cavity lesion or newly developing pleural effusion. Another eight patients had H1N1 pneumonia with co-infections. The following organisms were identified: Oxacillin-resistant Staphylococcus aureus (2), Pneumocystis jiroveci (1), Haemophilus parainfluenzae (3), Klebsiella pneumoniae (1), Streptococcus pneumoniae (2), and multiple-drug resistant Acinetobacter baumannii (1). Their CT scans showed diffuse or patchy areas of ground-glass attenuation mixed with consolidation but also revealed cyst/cavity lesions (3), centrilobular nodules (3), tree-in-bud opacity (4), mediastinal lymphadenopathy (6), and pleural effusion (4). These CT changes are definitely different from H1N1 monoinfection. The secondary infectious process may cause additional CT abnormalities. The possibility of H1N1 pneumonia with co-infections should be considered if there are CT findings other than pure H1N1 pneumonia.

Original languageEnglish
Pages (from-to)9-19
Number of pages11
JournalChinese Journal of Radiology
Volume36
Issue number1
Publication statusPublished - Mar 2011
Externally publishedYes

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H1N1 Subtype Influenza A Virus
Pandemics
Virus Diseases
Human Influenza
Pneumonia
Coinfection
Tomography
Pleural Effusion
Infection
Glass
Cysts
Haemophilus parainfluenzae
Pneumocystis carinii
Oxacillin
Acinetobacter baumannii
Klebsiella pneumoniae
Streptococcus pneumoniae
Staphylococcus aureus
Bacteria
Lung

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Clinical course and computed tomography abnormalities associated without and with concomitant infection in patients with pandemic influenza A (H1N1) 2009 virus infection. / Fu, Chen Ju; Chen, Huan Wen; Lin, Tzou Yien; Wong, Yon Cheong; Wang, Li Jen; Wan, Yung Liang; Wang, Chao Ran; Chen, Chien Cheng; Huang, Chung Guei; Ku, Yi Kang; Chen, Huan Wu.

In: Chinese Journal of Radiology, Vol. 36, No. 1, 03.2011, p. 9-19.

Research output: Contribution to journalArticle

Fu, Chen Ju ; Chen, Huan Wen ; Lin, Tzou Yien ; Wong, Yon Cheong ; Wang, Li Jen ; Wan, Yung Liang ; Wang, Chao Ran ; Chen, Chien Cheng ; Huang, Chung Guei ; Ku, Yi Kang ; Chen, Huan Wu. / Clinical course and computed tomography abnormalities associated without and with concomitant infection in patients with pandemic influenza A (H1N1) 2009 virus infection. In: Chinese Journal of Radiology. 2011 ; Vol. 36, No. 1. pp. 9-19.
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