The treatment strategy of acute respiratory distress syndrome (ARDS) or acute lung injury (ALI) is to get rid of the causing factor(s) as well as to offer lung protection aiming at reducing the complications of lung injury. In recent years, addition of spontaneous breath to positive pressure ventilation has become the main stream. Many studies have shown that application of biphasic positive airway pressure ventilation (BIPAP) /Airway Pressure Release Ventilation (APRV) in patients with ARDS can improve ventilation/perfusion ratio, reduce the use of sedative and muscle relaxants, increase oxygenation and decrease mean airway pressure, facilitate the recovery of injured lung, and prevent complications. Therefore, BIPAP is currently considered an important mode in ventilation support to patients with ARDS. The beneficial effects of BIPAP/APRV rendered its availability in new generation of ventilators. In order to meet the clinical demand, clinical staff members should understand the principle and physiologic effects of BIPAP. In addition, to optimize the therapeutic effects the staff members should make proper assessment of the patient and carries out appropriate adjustment. This review article focuses on the application of BIPAP /APRV in ARDS, covering the physiological influence, the effects on sedatives and muscles relaxants, and clinical practice.
|Original language||Traditional Chinese|
|Number of pages||9|
|Publication status||Published - 2008|
- spontaneous breath
- airway pressure release ventilation
- biphasic positive airway pressure ventilation