Clinical and radiographic spectrum of septic pulmonary embolism

K. S. Wong, T. Y. Lin, Y. C. Huang, S. H. Hsia, P. H. Yang, S. M. Chu

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Aims: To review the clinical presentation, radiographic findings, and outcome of therapy in children with septic pulmonary embolism. Methods: Retrospective analysis of patients in a tertiary paediatric facility in northern Taiwan. Results: Ten children were identified with septic pulmonary emboli in a four year retrospective chart review between 1998 and 2001. Seven were immunocompetent, two were premature infants, one had β thalassemia major. Seven had community acquired staphylococcal infections and bacteraemia, of which six were methicillin resistant Staphylococus aureus (MRSA) isolates. Five had soft tissue infections, two bone infections, one suppurative otitis media, one catheter related infection, and one unknown foci of infection. Multiple and bilateral nodular pulmonary parenchymal lesions were common on plain chest radiographs, but chest computed tomography scans showed the additional findings of a "vessel sign" and central cavitations, confirming the existence of septic pulmonary embolism. Conclusions: Community acquired MRSA infections occurred in seven patients with septic pulmonary embolism but without predisposing high risk factors. Critically ill children with skin, soft tissue, or bone infections, when associated with septic pulmonary embolism in an area with a high rate of MRSA, should be empirically treated with glycopeptides (such as vancomycin or teicoplanin) before susceptibility results are known, in order to minimise morbidity and avoid mortality.

Original languageEnglish
Pages (from-to)312-315
Number of pages4
JournalArchives of Disease in Childhood
Volume87
Issue number4
DOIs
Publication statusPublished - Oct 2002
Externally publishedYes

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Pulmonary Embolism
Methicillin Resistance
Infection
Thorax
Suppurative Otitis Media
Community-Acquired Infections
Teicoplanin
Bone and Bones
Staphylococcal Infections
Catheter-Related Infections
Lung
Soft Tissue Infections
Glycopeptides
beta-Thalassemia
Vancomycin
Bacteremia
Embolism
Taiwan
Critical Illness
Premature Infants

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Clinical and radiographic spectrum of septic pulmonary embolism. / Wong, K. S.; Lin, T. Y.; Huang, Y. C.; Hsia, S. H.; Yang, P. H.; Chu, S. M.

In: Archives of Disease in Childhood, Vol. 87, No. 4, 10.2002, p. 312-315.

Research output: Contribution to journalArticle

Wong, K. S. ; Lin, T. Y. ; Huang, Y. C. ; Hsia, S. H. ; Yang, P. H. ; Chu, S. M. / Clinical and radiographic spectrum of septic pulmonary embolism. In: Archives of Disease in Childhood. 2002 ; Vol. 87, No. 4. pp. 312-315.
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