Clinical analysis of Enterobacter bacteremia in pediatric patients: a 10-year study

Hui Lan Chen, Jen Her Lu, Hsin Hui Wang, Shu Jen Chen, Chun Jen Chen, Keh Gong Wu, Ren Bin Tang

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


BACKGROUND: Enterobacter species has emerged as an important pathogen of nosocomial bacteremia. The purpose of this study is to review the clinical characteristics of bacteremia in pediatric patients.

MATERIALS AND METHODS: We reviewed retrospectively the medical records of patients (under the age of 18 years) having Enterobacter bacteremia who were treated at Taipei the Veterans General Hospital from January 2001 to June 2011.

RESULTS: In total, 853 positive blood cultures were obtained from 620 patients during the study period. Among them, 96 episodes of Enterobacter bacteremia were found in 83 patients, accounting for 11.3% of all bacteremia. Eighty-two cases (98.8%) were nosocomial infections. Most of the cases were neonates (62 cases, 74.7%) and premature infants (51 cases, 61.5%). The common sources of bacteremia were the respiratory tract (53.0%), followed by intravascular catheter (10.8%), multiple sources (10.8%), and the gastrointestinal tract (8.4%). The overall case fatality rate was 18.1%, with the highest rate being reported among premature infants. The factors responsible for the deaths were leukocytosis and a higher median number of underlying diseases.

CONCLUSION: Based on the findings of the present study, it can be concluded that Enterobacter species are probably an important pathogen of nosocomial bacteremia in premature neonates. The number of underlying diseases should be considered a major factor influencing the prognosis.

Original languageEnglish
Pages (from-to)381-386
Number of pages6
JournalJournal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
Issue number5
Publication statusPublished - Oct 1 2014
Externally publishedYes


  • Bacteremia
  • Enterobacter
  • Neonates

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology and Microbiology(all)
  • Microbiology (medical)
  • Infectious Diseases


Dive into the research topics of 'Clinical analysis of Enterobacter bacteremia in pediatric patients: a 10-year study'. Together they form a unique fingerprint.

Cite this