Cleaved but not endogenous secretory RAGE is associated with outcome in acute ischemic stroke

Sung Chun Tang, Shin Joe Yeh, Li Kai Tsai, Chaur Jong Hu, Li Ming Lien, Giia Sheun Peng, Wei Shiung Yang, Hung Yi Chiou, Jiann Shing Jeng

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Objective: To investigate the expression patterns of 2 soluble isoforms of receptor for advanced glycation end-product (RAGE), including endogenous secretory RAGE (esRAGE) and cleaved RAGE (cRAGE), and their associations with outcome in acute ischemic stroke (IS). Methods: Acute IS patients (n = 106) and age- and sex-matched controls (n = 150) were recruited. Plasma levels of total soluble RAGE (sRAGE) and esRAGE in patients at

Original languageEnglish
Pages (from-to)270-276
Number of pages7
JournalNeurology
Volume86
Issue number3
DOIs
Publication statusPublished - Jan 19 2016

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ASJC Scopus subject areas

  • Clinical Neurology

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