Clear cell adenocarcinoma of the renal pelvis: An extremely rare neoplasm of the upper urinary tract

Kai Wen Liu, Victor Chia Hsiang Lin, I. Wei Chang

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Clear cell adenocarcinoma (CCA) in the urinary tract is a rare neoplasmmorphologically identical to the Müllerian counterpart. Clear cell adenocarcinoma is extremely rare in the upper urinary tract. We present a case with CCA of the renal pelvis. Microscopically, the tumor exhibited exophytic growth with predominantly tubulocystic structures, as well as solid and papillary patterns. The neoplastic cells were cuboidal with clear to pale eosinophilic cytoplasm and abundant intracellular and extracellular eosinophilic hyaline globules. By immunohistochemically, the tumor was labeled by cytokeratins and hepatocyte nuclear factor-1β. The patient was still alive without evidence of recurrence in the follow-up period of nineteen months after diagnosis.

Original languageEnglish
Pages (from-to)308-311
Number of pages4
JournalPolish Journal of Pathology
Issue number4
Publication statusPublished - Dec 1 2013
Externally publishedYes



  • Clear cell adenocarcinoma
  • Hepatocyte nuclear factor-1β
  • Renal pelvis
  • Upper urinary tract

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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