Circuit Integration Initiation of New Hippocampal Neurons in the Adult Brain

Chih Hao Yang, Adrian Di Antonio, Gregory W. Kirschen, Parul Varma, Jenny Hsieh, Shaoyu Ge

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Yang et al. show that prior to circuit integration, adult-born dentate granule cells undergo horizontal-to-radial transitioning, which is regulated by sphingolipid signaling via sphingosine-1-phosphate receptor 1.

Original languageEnglish
Pages (from-to)959-968.e3
JournalCell Reports
Volume30
Issue number4
DOIs
Publication statusPublished - Jan 28 2020

Keywords

  • adult hippocampal neurogenesis
  • circuit integration initiation
  • dentate granule cell
  • electrophysiological maturation
  • environmental enrichment
  • G protein-coupled receptor
  • hippocampus behavior-engaged activation
  • lipidomics
  • sphingosine-1-phosphate receptor 1

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Yang, C. H., Di Antonio, A., Kirschen, G. W., Varma, P., Hsieh, J., & Ge, S. (2020). Circuit Integration Initiation of New Hippocampal Neurons in the Adult Brain. Cell Reports, 30(4), 959-968.e3. https://doi.org/10.1016/j.celrep.2019.12.084