Chronic prostatitis and depressive disorder: A three year population-based study

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Abstract

Background: There is limited research on the relationship between chronic prostatitis (CP) and the subsequent risk of depressive disorders (DD). This population-based study aims to prospectively examine the relationship between a history of CP and the risk of developing DD in Taiwan. Methods: A total of 3051 adult patients, newly diagnosed with CP during 2001 to 2005, were recruited, together with 15,255 matched enrollees without a history of CP as a comparison cohort. All patients were tracked for a three year period from their index healthcare encounters to identify those who had subsequent DD. The Cox proportional hazards models were carried out to compute the risk of DD in the study and comparison cohorts, after adjustment for socio-demographic characteristics. Results: Of a total of 18,306 patients, 163 (5.34%) from the CP group and 494 (3.24%) from the comparison group had a subsequent diagnosis of DD during the follow-up period. Stratified Cox proportional analysis shows that, after adjusting for monthly income, geographic region, and urbanization level of the community in which the patient resided, hypertrophy (benign) of prostate, and urinary incontinence, the hazard ratio of DD during the three year follow-up period is 1.63 for patients with chronic prostatitis (95% CI = 1.36-1.96) than those without chronic prostatitis. The differences are most significant in the younger group, aged less than 30 years (hazard ratio, 2.50; 95% CI = 1.18-4.51). Conclusions: These results suggest that CP patients experience an increased risk of DD compared to non-CP patients during a three year follow-up period.

Original languageEnglish
Pages (from-to)404-409
Number of pages6
JournalJournal of Affective Disorders
Volume134
Issue number1-3
DOIs
Publication statusPublished - Nov 2011

Fingerprint

Prostatitis
Depressive Disorder
Population
Urbanization
Urinary Incontinence
Taiwan
Proportional Hazards Models
Hypertrophy
Prostate
Cohort Studies
Demography
Delivery of Health Care

Keywords

  • Chronic prostatitis
  • Depressive disorder
  • Epidemiology

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Psychology

Cite this

Chronic prostatitis and depressive disorder : A three year population-based study. / Chung, Shiu Dong; Huang, Chung Chien; Lin, Herng Ching.

In: Journal of Affective Disorders, Vol. 134, No. 1-3, 11.2011, p. 404-409.

Research output: Contribution to journalArticle

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