Chronic periodontitis and the subsequent risk of trigeminal neuralgia: A 5-year follow-up study

Joseph J. Keller, Jau Jiuan Sheu, Herng Ching Lin

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3 Citations (Scopus)

Abstract

Aim This study set out to explore the possibility that chronic periodontitis (CP) may also be a condition that could potentially result in secondary or symptomatic trigeminal neuralgia (TN) by utilizing a population-based dataset and cohort study design in Taiwan. Materials and Methods We included 110,104 subjects with CP in our study cohort, and randomly selected 110,104 subjects without a history of CP as a comparison cohort. We individually tracked each patient in this study for a 5-year period to identify those who received a subsequent diagnosis of TN. Results The incidence rate of TN during the 5-year follow-up period was 4.40 (95% CI = 3.87-4.98) per 10,000 person-years for subjects with CP, and 2.60 (95% CI = 2.20-3.05) per 10,000 person-years in comparison subjects. Cox proportional analysis revealed that the adjusted hazard ratio (HR) of TN during the 5-year follow-up period for subjects with CP was 1.65 (95% CI = 1.34-2.03) times higher than that of comparison subjects. However, the study subjects who had undergone a gingivectomy or periodontal flap operation did not have a higher adjusted risk of TN than comparison subjects (HR = 0.93, 95% CI = 0.54-1.61). Conclusion Our study detected a greater risk for TN among patients with CP than matched comparison subjects.

Original languageEnglish
Pages (from-to)1017-1023
Number of pages7
JournalJournal of Clinical Periodontology
Volume39
Issue number11
DOIs
Publication statusPublished - Nov 2012

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Chronic Periodontitis
Trigeminal Neuralgia
Gingivectomy
Cohort Studies
Taiwan
Incidence
Population

Keywords

  • chronic periodontitis
  • epidemiology
  • trigeminal neuralgia

ASJC Scopus subject areas

  • Periodontics

Cite this

Chronic periodontitis and the subsequent risk of trigeminal neuralgia : A 5-year follow-up study. / Keller, Joseph J.; Sheu, Jau Jiuan; Lin, Herng Ching.

In: Journal of Clinical Periodontology, Vol. 39, No. 11, 11.2012, p. 1017-1023.

Research output: Contribution to journalArticle

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