Chromosome Translocation in Peripheral Neuroepithelioma

Jacqueline Whang-Peng, Timothy J. Triche, Turid Knutsen, James Miser, Edwin C. Douglass, Mark A. Israel

Research output: Contribution to journalArticle

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Abstract

PERIPHERAL neuroepithelioma (peripheral neuroblastoma) is an uncommon malignant tumor of the peripheral nervous system with a histologic appearance similar to that of classical childhood neuroblastoma.1 2 3 In contrast to neuroblastoma, it typically presents in older children and young adults, it can be associated with peripheral nerves, and it spares the adrenal glands and sympathetic ganglia. We have studied both tumor specimens and tumor-cell lines from two patients with peripheral neuroepithelioma; in each case, we found these karyotypes to include an rcp(11;22)(q24;q12) indistinguishable from the one that has been reported in Ewing's sarcoma.4,5 This finding supports the hypothesis that these two entities.

Original languageEnglish
Pages (from-to)584-585
Number of pages2
JournalNew England Journal of Medicine
Volume311
Issue number9
DOIs
Publication statusPublished - Aug 30 1984
Externally publishedYes

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Peripheral Primitive Neuroectodermal Tumors
Neuroblastoma
Chromosomes
Nervous System Neoplasms
Sympathetic Ganglia
Peripheral Nervous System
Adrenal Glands
Tumor Cell Line
Karyotype
Peripheral Nerves
Young Adult
Neoplasms

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Whang-Peng, J., Triche, T. J., Knutsen, T., Miser, J., Douglass, E. C., & Israel, M. A. (1984). Chromosome Translocation in Peripheral Neuroepithelioma. New England Journal of Medicine, 311(9), 584-585. https://doi.org/10.1056/NEJM198408303110907

Chromosome Translocation in Peripheral Neuroepithelioma. / Whang-Peng, Jacqueline; Triche, Timothy J.; Knutsen, Turid; Miser, James; Douglass, Edwin C.; Israel, Mark A.

In: New England Journal of Medicine, Vol. 311, No. 9, 30.08.1984, p. 584-585.

Research output: Contribution to journalArticle

Whang-Peng, J, Triche, TJ, Knutsen, T, Miser, J, Douglass, EC & Israel, MA 1984, 'Chromosome Translocation in Peripheral Neuroepithelioma', New England Journal of Medicine, vol. 311, no. 9, pp. 584-585. https://doi.org/10.1056/NEJM198408303110907
Whang-Peng, Jacqueline ; Triche, Timothy J. ; Knutsen, Turid ; Miser, James ; Douglass, Edwin C. ; Israel, Mark A. / Chromosome Translocation in Peripheral Neuroepithelioma. In: New England Journal of Medicine. 1984 ; Vol. 311, No. 9. pp. 584-585.
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