Chromaligner

A web server for chromatogram alignment

San Yuan Wang, Tsung Jung Ho, Ching Hua Kuo, Yufeng J. Tseng

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Summary: Chromaligner is a tool for chromatogram alignment to align retention time for chromatographic methods coupled to spectrophotometers such as high performance liquid chromatography and capillary electrophoresis for metabolomics works. Chromaligner resolves peak shifts by a constrained chromatogram alignment. For a collection of chromatograms and a set of defined peaks, Chromaligner aligns the chromatograms on defined peaks using correlation warping (COW). Chromaligner is faster than the original COW algorithm by k2 times, where k is the number of defined peaks in a chromatogram. It also provides alignments based on known component peaks to reach the best results for further chemometric analysis.

Original languageEnglish
Article numberbtq337
Pages (from-to)2338-2339
Number of pages2
JournalBioinformatics
Volume26
Issue number18
DOIs
Publication statusPublished - Jun 23 2010
Externally publishedYes

Fingerprint

Web Server
Alignment
Servers
Warping
Metabolomics
Capillary Electrophoresis
Capillary electrophoresis
Chemometrics
High-performance Liquid Chromatography
Spectrophotometers
High Pressure Liquid Chromatography
High performance liquid chromatography
Electrophoresis
Resolve

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Computational Theory and Mathematics
  • Computer Science Applications
  • Computational Mathematics
  • Statistics and Probability
  • Medicine(all)

Cite this

Chromaligner : A web server for chromatogram alignment. / Wang, San Yuan; Ho, Tsung Jung; Kuo, Ching Hua; Tseng, Yufeng J.

In: Bioinformatics, Vol. 26, No. 18, btq337, 23.06.2010, p. 2338-2339.

Research output: Contribution to journalArticle

Wang, SY, Ho, TJ, Kuo, CH & Tseng, YJ 2010, 'Chromaligner: A web server for chromatogram alignment', Bioinformatics, vol. 26, no. 18, btq337, pp. 2338-2339. https://doi.org/10.1093/bioinformatics/btq337
Wang, San Yuan ; Ho, Tsung Jung ; Kuo, Ching Hua ; Tseng, Yufeng J. / Chromaligner : A web server for chromatogram alignment. In: Bioinformatics. 2010 ; Vol. 26, No. 18. pp. 2338-2339.
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