Chemistry and biochemistry of the streptovaricins. XII. Atropisomeric streptovaricins

Kenneth L. Rinehart, Waltraut M.J. Knoll, Katsumi Kakinuma, Frederick J. Antosz, Iain C. Paul, Andrew H.J. Wang, Fritz Reusser, L. H. Li, William C. Krueger

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

The streptovaricins (and other ansamycin antibiotics)3 derive an intrinsic helicity from their ansa rings. In connection with extensive studies of the biological activities of the streptovaricins and their derivatives, 2 we have examined the effect of this helicity on the activities displayed.

Original languageEnglish
Pages (from-to)196-198
Number of pages3
JournalJournal of the American Chemical Society
Volume97
Issue number1
DOIs
Publication statusPublished - Jan 1 1975
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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